Post-partum Psychiatric Disorders Flashcards

1
Q

PostPartum blues

A

Postpartum (PP) blues: Low mood and mild depressive symptoms that are transient and self-limiting and are common in the perinatal period

They usually start 5 days after delivery and may last 1-2 weeks.

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2
Q

PostPartum depression

A

PP depression: depressive symptoms beginning within the 1st 12 months following childbirth and lasting for at least 2 weeks

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3
Q

PostPartum psychosis

A

PP psychosis: a psychiatric manifestation with abrupt onset after delivery that is characterized by psychotic symptoms

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4
Q

Risk factors

A

° Young age (< 25 years)

° Poor social support

° Difficulties with breastfeeding

° Cesarean sections, traumatic birth experience, or other perinatal complications

° Women with infants having health problems and/or with infants admitted to the NICU

° History of psychotic illnesses (especially anxiety and depression)

° Family history of psychiatric illnesses

° Previous episode of PP psychiatric disorder

° Stressful life events (during pregnancy and near delivery)

° Childcare stress (e.g., inconsolable crying infant)

° History of sexual abuse

° Financial difficulties

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5
Q

PostPartum blues typical symptoms

A

° The woman worrying that she will not make a good mother.

° Fears that her baby might die

° Anxious

° Agitation, restlessness, and tearful
° Insomnia
° Irritable
° Poor appetite

Feeling guilty and/or overwhelmed (especially about being a mother)

° Crying, sadness

° Rapid changes in mood and irritability

° Anxiety

° Poor concentration

° Eating too much or too little

° Insomnia or frequent awakenings at night

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6
Q

Management of postpartum blues

A

° Resolves spontaneously

° Provide reassurance.

° Encourage self-care.

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7
Q

Major risk for PostPartum depression

A

° Prior depression

° Hormonal changes during the puerperium

° Sleep deprivation

° Genetic susceptibility may contribute .

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8
Q

Risj factors for PostPartum depression

A
  1. History of depression

° Personal history of depression

° History of depression during pregnancy

° History of postpartum depression

° Family history of depression

  1. Recent stressful life events (unemployment of partner)
  2. Partner with depression
  3. History of mood changes associated with menstrual cycles or contraceptions use
  4. Daily stressors ( such as child care, lack of social support / financial especially from the partner, and family)
  5. Unintended pregnancy
  6. Baby blue
  7. Previous history or current poor obstetric outcomes ( miscarriage, preterm delivery, congenital malformation.)
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9
Q

Presentation for PostPartum depression

A

° Disinterest in self, in child, and in normal activities

° Feeling isolated, unwanted, or worthless

° Feeling a sense of shame or guilt about parenting skills

° ↑ Anger outbursts

° Suicidal ideation or frequent thoughts of death

° Tearfulness
° Insomnia or increased sleeping 
° Extreme fatigue 
° Appetite disturbance 
° Headaches and back aches that do not resolve with Analgesics 
° Extreme sadness
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10
Q

DSM-V criteria for major depressive disorder with peripartum onset:

A

A. Patients must meet at least 5 out of 9 symptoms for>2 weeks.

B. Depressed mood or anhedonia (reduced pleasure from previously enjoyable habits) must be among the patient’s symptoms.

C. Symptoms include:

° Depressed mood, almost everyday

° Anhedonia

° Appetite/weight changes (↓ or ↑)

° Sleep disturbances (↓ or ↑)

° Psychomotor agitation or retardation (patient is anxious and moves a lot, or barely moves)

° Loss of energy/fatigue

° Feeling worthless or excessively guilty

° Trouble concentrating

° Suicidal ideation and/or attempts

D. Symptoms cause a significant decline in function in social and occupational/school settings.

E. The patient does not have a history of:

° Other psychiatric disorders (especially bipolar disorder)

° Substance use

° Medical conditions such as hypothyroidism, nutritional deficiency, and cerebrovascular disease, which cause depressive mood

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11
Q

Limitations of the DSM-V criteria:

A

° Many symptoms, especially weight changes and sleep disturbances, are common and frequently unrelated to depression in the PP period.

° Restricts the diagnosis to symptoms beginning within 4 weeks of delivery → may lead to underdiagnosis

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12
Q

Laboratory studies for PP D:

A

° If patientsdohave a history of medical conditions known to cause depressive symptoms, tests should be ordered to assess status.

° Should be ordered if patients have other findings consistent with these conditions (e.g., new-onset constipation and goiter, which are suggestive of hypothyroidism)

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13
Q
  1. General Measures for PostPartum depression
A

° Mothers should be taught to recognize symptoms of depression, which they may mistake for the normal effects of new motherhood

E.g- fatigue, difficulty concentrating.

° Admission maybe necessary for severe postpartum depression

° Psychoeducational or support groups
*for mother with mid to moderate symptoms also those that don’t wish to take medication and want to breastfeed.

° Exercise therapy

° Massage therapy

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14
Q

2.General Measures for PostPartum depression

A

° Maintain an empathic and concerned attitude.

° Discuss uncertainty with a specialist at any point in the care pathway.

° Assess severity of the condition and suicide risk.

° Exclude and optimise treatment of underlying and/or comorbid medical conditions (e.g. hypothyroidism, anaemia, HIV/AIDS, TB, cancers, diabetes).

° Screen for and manage underlying or comorbid substance use, e.g. nicotine, alcohol, over the counter analgesics, benzodiazepines.

° Screen for bipolar disorder and comorbid psychiatric disorders – refer for specialist assessment.

° Explore and address psychosocial stressors:

  • Stress management/coping skills – refer for counselling.
    • Relationship and family issues – refer for counselling Refer to a social worker if abuse is evident.

° Provide self-help literature, where available, and refer to local support

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15
Q

Complications for PostPartum depression

A

° Risk of impaired maternal-child bonding → risk of behavioral problems and/or developmental delay in the infant

° ↑ Risk of developing major depressive disorder later in life

° Suicide (preventable with adequate treatment)

° Infanticide

° Father depression

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16
Q

PPD Medicine treatment First line

A

° It is important to ask for suicide risk in these patients

• Fluoxetine, oral, Initial dose: 20 mg

If there is no or partial response after 4–6 weeks, increase to 40 mg, if the is no change move to 2nd line

17
Q

PPD Medicine treatment Second line

A
  • Citalopram, oral, Initial dose: 20 mg

* Review the mother at 4 weeks and 6 weeks if she reports improvement. continue with the same dose

18
Q

PPD Medicine treatment 3rd line

A
  • If a sedating antidepressant is required
  • Amitriptyline, oral, at bedtime.
  • Initial dose: 25 mg per day.
  • Increase by 25 mg per day at 3–5 day intervals.
  • Maximum dose: 150 mg per day.

•If no response: discuss with a specialist (re-evaluate diagnosis, repeat general measures, prescribe alternative SSRI, psychotherapy, or ECT).

19
Q

Postpartum psychosis

A
  • Is the most severe form of postpartum psychiatric illness.
  • It is a psychiatric emergency.
  • At highest risk are women with personal history of bipolar disorder or previous episode of postpartum psychosis.
  • In most women, symptoms develop within the first 2 weeks.
20
Q

Symptoms of Postpartum psychosis

A
  • Hallucinations
  • Delusions– usually centering around the baby
  • Illogical thoughts
  • Attempts to kill the baby (infanticide)
  • Insomnia
  • Memory impairment
  • Confusion
  • Irritability
  • Suicidal wishes or attempts to kill one-self
  • Poor hygiene and mother will look dehydrated
  • Fatigue
  • Agitation/feeling of anxiety
  • Disorientation
  • May have a fever which may be associated with puerperal sepsis
  • There may be breast engorgement from days of not breastfeeding
21
Q

General Measures of Postpartum psychotic disorder

A
  • Always admit a psychotic mother
  • Ensure safety of the staff, patient and infant
  • Sedate if necessary
  • Ensure constant supervision of mother and baby to avoid harm to the baby but if baby is at severe risk keep it away from the mother.
  • Counsel and give support to the spouse or relatives and involve them in care of mother and baby.
22
Q

Aim of treatment in Postpartum psychotic disorder

A

Aim of treatment:

  • Reduce depression
  • Stabilize the mood
  • Reduce psychosis
23
Q

Breastfeeding & Psychotropic Medication

A
  • Women who plan to breastfeed must be informed that all psychotropic medications, including antidepressants, are secreted into breast milk.
  • Women treated with valproic acid & carbamazepine should avoid breastfeeding, because these agents have been associated with hepatotoxicity in the infant.
  • Avoid breastfeeding in premature infants or in those with hepatic insufficiency who may have difficulty metabolizing medications present in breast milk
24
Q

Medicine treatment for Postpartum psychotic disorder

A
  • If there is fever look for signs of infection and watch out for delirium (refer to topic of Neurocognitive disorders).
  • Haloperidol, oral, Initial dose: 0.5 mg daily, increasing to 5 mg daily.

OR

  • Risperidone, oral, Initial dose: 2–3 mg daily.
  • Give antibiotics in case of puerperal sepsis