PoS Flashcards
Contraindications to thrombolysis (STEMI)
active internal bleeding recent haemorrhage, trauma or surgery (including dental extraction) coagulation and bleeding disorders intracranial neoplasm stroke < 3 months aortic dissection recent head injury pregnancy severe hypertension
Side effects
Haemorrhage
Hypotension - more common with streptokindase
Allergic reactions may occur with steptokinase
Stroke syndromes symptoms
- Primary intracerebral Haemorrhage
Headache
Vomiting
LOC
Stroke syndromes symptoms
Total anterior circulation infarcts (TACI)
Involves middle and anterior cerebral arteries
Hemiparesis
Homonymous Hemianopia
Higher cognitive dysfunction - Dysphasia
Stroke syndromes symptoms
Partial anterior circulation infearcts (PACI)
Involves smaller arteries of anterior circulation e.g. upper or lower division of middle cerebral artery
Higher cognitive dysfunction or two of the three TACI features
Stroke syndromes symptoms Lacunar infarcts (LACI)
Involves perforating arteries around the internal capsule, thalamus and basal ganglia
Present with either isolated hemiparesis, hemisensory loss or hemiparesis with limb ataxia
Stroke syndromes symptoms
Posterior circulation infarcts (POCI, c. 25%)
Vertebrobasilar arteries
Presents with features of brainstem damage
Ataxia, disorders of gaze and vision, cranial nerve lesions
Stroke syndromes symptoms
Pontine
VI nerve: horizontal gaze palsy
VII nerve
Contralateral hemiparesis
Stroke syndromes symptoms Lateral medulla (posterior inferior cerebellar artery)
Ipsilateral: ataxia, nystagmus, dysphagia, facial numbness, cranial nerve palsy
Superior orbital fissure syndrome Results in?
Complete opthalmoplegia and ptosis (Cranial nerves 3, 4, 6 and nerve to levator palpebrae superioris)
Relative afferent pupillary defect
Dilatation of the pupil and loss of accommodation and corneal reflexes
Altered sensation from forehead to vertex (frontal branch of trigeminal nerve)
Structures passing thorugh SOF
Long Fissures Seem To Store Only Nerves, Instead Of Arteries, Including Ophthalmic Veins
The order of the contents passing through the superior orbital fissure form superior to inferior:
L: lacrimal nerve (branch of CN V1)
F: frontal nerve (branch of CN V1)
S: superior ophthalmic vein (tributary to cavernous sinus)
T: trochlear nerve (CN IV)
SO: superior division of the oculomotor nerve (CN III)
N: nasociliary nerve (branch of CN V1)
IO: inferior division of the oculomotor nerve (CN III)
A: abducens nerve (CN VI)
IOV: inferior ophthalmic vein (tributary to both cavernous sinus and pterygoid venous plexus)
Indications for hemicranieotomy?
Age under 60 years
Clinical deficit in middle cerebral artery territory
Decreased consciousness
>50% territory infarct