portal Hypertension And Crohosis Flashcards
True or false
Portal HTN Lead to cirrhosis
False
Cirrhosis lead to portal HTN
What the causes of cirrhosis ?
Chronic drinking alcohol and viral hepatitis C
True or false
Women more quickly develop alcoholic cirrhosis than men
True
Why? Because women metabolizs less alcoholic in the GI tract
That allowing delivery of more ethanol to liver ( directly hepatotoxic )
What’s the accumulate bilirubin cause ?
○Jaundice ( yellowing of the skin)
○Scleral icterus ( yellowing of the sclera )
○Tea colored urine
Increased intrahepatic resistance to portal bloof flow cause ?
Enlarged spleen
True or false
The most common condition associated with cirrhosis is HE
False
Ascites
Low serum albium levels can elevated ?
Hydrostatic pressure and increase capillary permeability allow fluid to leak from the vascular space into body tissues
Result : ascites, perpheral edema, fluid in the pulmonary system
True or false
Cirrhotic change lead to hypoalbuminemia
True
Because decrease in synthetic function
True or false
Usually SBP with polymicrobial infection
False
Rarly
What’s the most common gram negative bacterial infection in SBP?
Escherichia coil (E.coli)
Klebsiella pneumonia
What’s the most common gram positive bacteria in SBP?
Streptococcus pneumonia
Cirrhosis and portal HTN cause?
Ascites
Hepatorenal syndrome
Varices
SBP
Hepatic encephalopathy
What’s the less common causes of cirrhosis
Genetics and metabolic risk factors
Primary biliary cirrhosis
Nonalcoholic fatty liver disease
Heteditary hemochromatosis ( high level of iron)
Wilson disease ( high level of cupper )
Alpha antitrypsin deficiency
What’s the marker for encephalopathy ?
Decreased cognition
Confusion
Change in behavior
Asterixis
Patients with SBP Present with:
Fever
Painful tympanic abdomen
Changes in mental status
True or false
Sign of ascites is increased abdominal girth
True
Abdominal girth قطر البطن
What’s the maximium dose of acetaminophen use in patient with cirrhosis
Not exceed 2 g daily
Mention types of vaccination give for patient with cirrhosis
○Hepatitis A, B vaccination
○Pneumococcal and influenza vaccination
