IBD Flashcards

1
Q

True or false
Smoking reduces the risk of UC

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

True or false
Those medications are not effective in increasing the risk of IBD NSAIDs and oral contraceptives

A

False
Those are increasing risk of IBD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

True or false
Smoking are worsen CD

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Which is the correct answer
A) inflammation in UC is discontinuous and confluent
B) inflammation in UC superficial and does not typically extend below the submucosal layer of GI tract
C) inflammation in CD may be transmural
D) CD affects all parts of the entire GI tract from mouth to anus

Answer :
A) all above is correct
B) B+C
C) All is incorrect
D) All is correct except A

A

Answer : B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Which sign in UC is the difference from CD
A) TACHYCARDIA
B) fever
C) hemorrhoids
D) arthritis

A

Answer
C

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What’s the example for joint complications of extraintestinal manifestation of IBD

A

Anklosing spondylitis and sacroilitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What’s the example for ocular complications of extraintestinal manifestation of IBD

A

Episcleritis and uveitis and iritis
Blurred vision, eye pain, photophobia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What’s the example for skin complications of extraintestinal manifestation of IBD

A

Pyoderma gangrenosum and erythema nodosum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What’s the example for liver complications of extraintestinal manifestation of IBD

A

Gallstone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Which medication used in acute flare up
A) mesalamine
B) budesonide
C) metronidazole
D) Azathioprine

A

B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Which medication useful for maintaining remission of IBD and reducing the need for long term Corticosteroids
A) Azithioprine
B) 6-mercaptopurine
C) inflximab
D) methylprednisolone
E) A+B
F) A+B+C except D

A

E

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Immunosuppressant medication:

A

6-mercaptopurine
Azathiopurine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Idiosynocratic effect of sulfapyridine

A

bone Marrow suppresion
Hepatitis
Hypersensivity reaction
Pulmonitis
Reduction in sperm count in males

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Side effects dose related of sulfapyridine

A

Headache
Dyapepsia
Nausea
Vomiting
Fatigue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Side effect of 6-mercaptopurine and Azathiopurine

A

Hypersensivity reactions resulting in :
Pancreatitis
Fever
Rash
Hepatitis
Leukopenia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

MOA OF methotrexate

A

Folate antagonist

17
Q

SE of methotrexate

A

Hepatotoxicity
Pulmonary fibrosis
Bone marrow suppression

18
Q

True or false
Some patients present with extraintestintal manifestaions after GI symptoms

A

False
Before
ممكن تكون عندك اعراض

19
Q

True or false
Some patients present with extraintestintal manifestaions after GI symptoms

A

False
Before
ممكن تكون عندك اعراض

20
Q

Which is more bleedy diarrhea ?

21
Q

Which disease have tensmus symptoms ?

22
Q

What’s mean tenesum?

A

The feeling that you need to pass stools even through your bowels are already empty

23
Q

True or false
Biologic agent increase risk of serious infections.

A

False
Reactivation not increase

24
Q

Medications should avoided in IBD

A

●Anticholinergic : hycscyamine - dicyclamine
●Antidiarrhea
Loperamide - diphenoxylate/atropine - codeine
●NSAIDs

25
Treatment In Acute severe UC :
Methylprednisolone 40-60mg IV per day
26
Patient not respond to IV methylprednisolone In acute severe acute UC what's the alternative ?
Infliximab as single dose or cyclosporine (given as a continuous IV infusion )
27
True or false Corticostetoids are effect for maintaining remission
False
28
What's oral mesalamine dose can be in maintenace and remissiom in combination with topical ?
2-4g Sulfasalazine or 2-2.4g mesalamine