porphyrias Flashcards
1
Q
Porphyria cutanea tarda is deficiency in what enzyme?
A
Uroporphyrinogen decarboxylase, found in the cytoplasm and converts uroporphyrinogen III to coproporphyrinogen III.
2
Q
Porphyria cutanea tarda is associated with what viral infection
A
Hep C
3
Q
Porphyria cutanea tarda is often triggered by ingestion of what kinds of substances
A
Ethanol, estrogens.
4
Q
Clinical fx of porphyria cuteness tarda
A
Painless blisters, hypertrichosis, and hyperpigmentation (esp of face)
5
Q
Tx of porphyria cutaneous tarda
A
Phlebotomy or hydrochloroquine as well as IFN alpha if patient is connected with Hep C
