Population Genetics

Question 1

What is Pop Gen

Answer 1

study of allele and genotype frequency

Question 2

Population

Answer 2

every member with selected characteristic

Question 3

Sample

Answer 3

subset which represents whole pop,
unrelated
chosen at random

Question 4

locus

Answer 4

specific pos of specific c/s

Question 5

allele

Answer 5

alt form of gene or marker at a specific locus

Question 6

genotupe

Answer 6

genetic makeup of an induv @ specific gene

Question 7

phenotype

Answer 7

observable characteristics due to genetic and environment

Question 8

Hardy weinberg

Answer 8

if a pop is at genetic equilibrium, allele frequency will not change,

p + q = 1
p2 +2pq + q2= 1

Question 9

polymorphism

Answer 9

Blood groups

M and N antigens are at one locus, S and s are at another

Question 10

Allele frequency

Answer 10

c/s that contain a specific allele

allele at a locus can be determined by sequencing

Question 11

Autosomal recessive

Answer 11

freq of disease causing allele 1 is derived from incidence of the disease in the pop.

allows for estimation of allelic and carrier freqe

incidence is found from epidemiology

Question 12

HW Equilibria Rules

Answer 12

Pop is indefinitely large
random mating
no migration
no natural selection
no mutation

NO TRUE OF HUMAN POP BUT GIVES ESTIMATE

Question 13

X Linked conditions

Answer 13

For females carrier incidence is 2pq

for males, freq is q= disease freq