Polynucelotides and DNA Flashcards

1
Q

how do nucleotides join up together

A

join up between the phosphate group on on e nucleotide and the sugar of another via a CONDENSATION reaction

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2
Q

what is a phosphodiester bond

A

one phosphate group bonded to two ester bonds

a chain of these forms a sugar phosphate backbone

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3
Q

how many hydrogen bonds form between A=T

A

2

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4
Q

how many H bonds between C=G

A

3

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5
Q

how would you describe the DNA helix

A

two polynucleotide strands
running antiparallel to eachother
that twist to form a DNA double helix

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6
Q

what is the 1st step of DNA replication

A

Dna helicase breaks the hydrogen bonds between the polynucleotide strands, causing the helix to unzip

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7
Q

2nd DNA replication

A

each original strand acts as a template for a new strand

free dna nucleotdes attach to exposed bases on each template strand by complemntary base pairing

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8
Q

3rd DNA replication

A

Dna polymerase joins the nucleotides of the new strand together, forming a sugar phosphate backbone

hydrogen bonds form between bases on the original and new strand. they twist to form a double helix

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9
Q

4th dna replication

A

each new DNA molecule has one strand from the original DNA and one new strand.

this is know as SEMI CONSERVATIVE REPLICATION

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10
Q

why does DNA replication have to be accurate?

A

to make sure genetic information is conserved

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11
Q

what is mututation

A

a mutation is any change to the DNA base sequence

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12
Q

why could a mutation be bad

A

could alter the amino acid sequence of a protein

which could even lead to the production of abnormal protein

however this may not be a bad thing because the abnormal might function better/worse/not at all

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