Polymyositis ☺️ Flashcards
1
Q
Epidemiology
Etiology and pathophysiology
A
Middle aged females
Idiopathic/associated with connective tissue disorders/malignancy
Type 4 hypersensitivity against muscle fibres
2
Q
Presentation of polymyositis and dermatomyositis
Skin features specific to dermatomyositis
A
Symmetrical proximal muscle weakness +- tenderness
Raynaud’s
Resp muscle weakness, ILD
Dysphagia, dysphonia
Skin features specific to dermatomyositis
- photosensitivity
- heliotrope rash around eyes
- macular rash on back, shoulders
- Gottron’s papules
- nail fold capillaries
- Dry, scaly hands with cracks on palmar, lateral fingers
3
Q
Investigations
- findings in polymositis
- additional findings in dermatomyositis
A
High CK, LDH, AST, ALT, aldolase
Anti synthetase, Jo1 AB
EMG
Muscle biopsy
ANA
4
Q
Management
A
Prednisolone
