Poly/dermatomyositis

Question 1

What is the key investigation for polymyosistis and dermatomyositis?

Answer 1

Creatinine kinase

Question 2

Dermatomyositis and polymyositis can be caused by an underlying malignancy making them ___ syndromes

Answer 2

Paraneoplastic

Question 3

Presentation of polymyositis and dermatomyositis (4)

Answer 3

Muscle pain
Bilateral, proximal
Mostly affecting shoulder and pelvis
Develops over weeks

Question 4

Difference between dermatomyositis and polymyositis

Answer 4

Polymyositis is muscle involvement

Dermatomyositis is muscle and skin involvement

Question 5

Dermatomyositis skin features (5)

Answer 5

Gottron lesions (scaly red patches) on knuckles elbows and knees

Photosensitive erethematous rash

Purple rash on face and eyelids

Periorbital oedema

Calcium deposits in skin

Question 6

Autoantibodies is polymyositis and dermatomyositis (3)

Answer 6

Anti Jo 1 (poly and derm)

Anti Mi 2 (derm)

Anti nuclear (derm)

Question 7

Diagnosis of dermatomyositis and polymyositis based on (5)

Answer 7

Clinical presentation

Creatinine kinase

Autoantibodies

Electromyography

Muscle biopsy

Question 8

First line management of polymyositis and dermatomyositis

Answer 8

Corticosteroids