Polioencephalomalacia PEM

Question 1

What are the 2 dietary risks?

Answer 1

Reduced thiamine absorption in response to high thiaminase activity in the reticulo-rumen
High sulphide/sulphate intake leading to production of hydrogen sulphide in the reticulo-rumen

Question 2

What dot eh 2 conditions cause in the body?

Answer 2

result in reduced ATP production due to inhibition og the TCA cycleand ETC due to low levels of thiamine or high levels of sulphide

Question 3

What do animals with subacute cases do?

Answer 3

Separate from the group, stop eating, display twitches of ears/face, head held in elevated position, cortical blindness with absence of menace response with normal papillary light reflex and followed by recovery with only a few minor neurologic impairments

Question 4

What do animals with acute cases do?

Answer 4

Blindness followed by recumbency, tonic/clonic seizures and coma usually poor response to therapy and high mortality