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ayyyy > polimiositis/dematomiositis > Flashcards

polimiositis/dematomiositis Flashcards

1
Q

que es

A

Enfermedad inflamatoria del músculo de causa autoinmune asociado con otras enfermedades del tejido conjuntivo y neoplasias.

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2
Q

que afecta

A

musculatura respiratoria, corazon, faringe y laringe

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3
Q

etiologias

A
  • Coxackie
  • VIH
  • Hep B
  • Infleunzae
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4
Q

epidemio

A

mujeres
polimiositis - niños 5-15 años
dermatomiositis - adultos 45-65 años

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5
Q

asociado a genes

A

haplotipo HLA B8, HLADR3

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6
Q

clinica

A

Debilidad progresiva muscular iniciando por la parte más proximal
- Cintura escapular
- Cintura pélvica
- Cuello, faringe y laringe

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7
Q

criterios dx

A
  1. Debilidad simétrica proximal, progresando durante semanas o meses
  2. Biopsia muscular que evidencia una miopatía inflamatoria
  3. Aumento de los niveles séricos de enzimas musculares
  4. Hallazgos electromiográficos de miopatía
  5. Erupción cutánea típica de dermatomiositis
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7
Q
A
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8
Q

dermatomiositis

A

mujeres, niños, jovenes, con afeccion cutanea,

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9
Q

neoplasias associadas a dermatomiositis

A

ca ovario, pulmon, pancreas, estomago, colon, recto,

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10
Q

clinica de dermatomiositis

A

exantema + signo de gottron

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11
Q

dx de dermatomiositis

A

biopsia muscular

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12
Q

polimiositis

A

mujeres, adultas, SIN AFECCION CUTANEA,

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13
Q

polimiositis a que neoplasias se asocia

A

ca pulmon, vejiga, LNH

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14
Q

clinica de polimiositis

A

mialgias + debilidad facial leve

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15
Q

dx de polimiositis

A

biopsia muscular

16
Q

tratamiento para poli/dermatomiositis

A

no grave - prednisona + Azatioprina o MTX

grave - metilprednisona + ciclofosfamida

17
Q

miositis de cuerpos de inclusion

A

HOMBRES, >50 años, CRONICO, ASIMETRICO, PROXIMAL O DISTAL

18
Q

miositis no se asocia a cancer

A

verdadero

19
Q

clinica miositis

A

debilidad + atrofia muscular lenta progresiva

20
Q

tx de miositis

A

inmunoglobulina IV

ayyyy (5 decks)

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