Poisoning ☠️ Flashcards
Causes of small pupil in poisoning
OPC : Opioids, OPC,Clonidine (দিনের আলোয় পিউপিল ছোট)
Causes of large pupil
TCA ( TCA,Cocaine,Amphetamine)
Poisons causing rhabdomyolysis-
Amphetamine,Caffeine
Poisons causing hyperthermia-
Ecstasy,SSRI,Salicylates
Poisons causing hypothermia-
CNS Depressant,
Opioids,
Chlorpromazine
Highly toxic antibiotics-
Tetracycline, Anti-tb drugs
Causes of toxins causing normal lactate acidosis:
“Sally met harry para gliding”
Sally=Salicylates
Met harry=Methanol
Para= Paraldehyde
Gliding=Glycol
Causes of high lactate acidosis (toxin+non toxin):
High MISS COC
High= High lactate gap
M= Metformin
I= Iron
S= Sodium Valproate
S= Shock ( non toxic cause)
CO= Carbon Monoxide
C= Cyanide
Common toxic causes of anion gap:
Alcoholic Annie Sells Cyan Irons
Alcoholic= Ethanol,Methanol,Glycol
Annie= Anion gap
Sells= Salicylates
Cyan= Cyanide
Irons= Iron
Common causes of Osmolar gap:
Alcoholic Annie is awesome-
3 alcohols cause osmolar gap: Ethanol Methanol Glycol
Causes of Methaemoglobinaemia:
Myth is DON is BAC
D= Dapsone
O=Organic Nitrites
N=Nitrates, Naphthalene
B=Benzocaine
A=Aniline dye
C=Chloroquine, Chlorobenzene, Copper Sulphate
Consequences of Methaemoglobinaemia:
1)Oxy-hb curve shifted to left ( because methb tightly bound to O2 and doesn’t let go)
2)Reduced O2 in tissues
(When curve is shifted to left, tissue is left behind)
3) C: Cyanosis-> SOB-> fatigue
Chest pain
Confusion
Consciousness impaired
Convulsion
Treatment of Methaemoglobinaemia:
-Methylthioninium chloride ( Methylene Blue)
When skin is blue (cyanosed) treat with blue
In Methaemoglobinaemia, SpO2 in pulse oximetry tends towards-
85%
• Activated charcoal is most effective if given within-
1 hour