Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

MedNeuro Block 1 > Podcast reviews > Flashcards

Podcast reviews Flashcards

1
Q

Brain Capillaries have what kind of polarity?

A

Endothelial:

Basal and Apical

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Route of transport in brain

A

tight junctions: keeps cellular route intracellular

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Three components to BBB

A

basal lamina
pericytes
astrocyte foot processes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

cover abluminal surface (surface that faces away from capillary lumen or towards the brain)

A

astrocyte foot processes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Cells that have sm. muscle properties

A

pericytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Tight junctions limits mvmt of what type of agents

A

Tight jnx limit movment of water soluble agents

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What pathway allows O2, CO2 and drugs and other lipophilic molecules?

A

Transcellular

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Receptor mediated transcytosis use __________ and ________

A

insulin and transferrin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the process of transcytosis?

A

Plasma proteins (albumin) get surrounded by Cations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Can glucose move against the conc gradient?

A

No: its is non-E dependent

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the metabolic barrier in the brain?

A

Enz system specific to BBB regulate composistion of brain interstial fluid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Astrocyte foot processes surround which surface?

A

Albuminal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are the 3 functions of astrocytes?

A
  1. Regulate tight jnx (physical)
  2. Influence expression and polarization of transporters (transporter)
  3. Influence expression of enZ systems (metabolic)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

How can you disrupt the BBB?

A

Down regulate proteins in tight jnx, break down basil lamina, influence secretion of proteins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What pathology is the BBB absent from?

A

brain tumors–thus amendable to chemotherapy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Methods to disrupt BBB

A

Stroke/trauma/infection/MS/HIV/Alzeihmers disease/Parkinsons/Epilepsy/Tumor/Pain

17
Q

What organs lack a BBB

A

Circumventricular organs

18
Q

Sensory receptors here require access to blood to monitor blood so it can send signal to ant. Pit for homeostasis purpose

A

Median eminense

19
Q

6 Circumventricular Organs

A 
area postrima
pineal gland
Choroid plexus of third ventricle
Subfornical organ
vascular organ of lamina terminalis
Median Eminense
20
Q

BBB have less/more pinocytotic vesicles

A

less

21
Q

BBB has ________ and capilary has _________

A

tight…. gap

22
Q

Veins of the Cerebrum have valves/no valves and are in how many groups?

A

No valves, 2 groups

23
Q

What drains superolateral and medial surfaces of cerebral hemis?

A

Superficial Superior Vein

24
Q

Where does the superficial superior vein empty into?

A

Superior Sagittal Sinus

25
Q

What veins join the superior sagittal sinus at right angles?

A

Anterior superficials

26
Q

What is the direction of blood flow?

A

angles are significant; blood flow it anterior→posterior

27
Q

What keeps posterior veins from collapsing?

A

pressure keeps posterior veins from collapsing

28
Q

Where is the superficial middle vein located?

A

In the Sylvian fissure

29
Q

What does the superficial middle vein drain?

A

Lateral surface of cerebral hemisphere

30
Q

Where does the superficial middle vein empty into?

A

Cavernous sinus

31
Q

Where is the Superficial inferior vein located?

A

on Orbital surface of Frontal lobe + Inferior surface of temporal lobe

32
Q

What two veins does the Superficial inferior vein turn into?

A

Orbital vv

Temporal vv

33
Q

Orbital vv empties to :

A

Superior Sagittal Sinus

34
Q

Temporal vv empties into:

A

Cavernous sinus (via middle cerebral veins)

35
Q

Superior Anastomotic Veins connects what to what?

A

-Connect Superficial Middle Cerebral w/ Superior Sagittal Sinus
Called veins of Trolard

36
Q

Inferior Anastomotic Veins (of Labbe) connects:

A

Connect Superficial Middle to Transverse sinus

37
Q

Inferior Anastomotic Veins (of Labbe) runs over

A

runs over temporal lobe

38
Q

Basal vein is made up of what two veins?

A

Anterior cerebral vein (drains medial aspect of cerebral hemis) + deep middle cerebral vein (drains insula and surrounding gyri)
-drains medial aspect of cerebral hemis

MedNeuro Block 1 (6 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions