PoD Formative

Question 1

Which antibiotic inhibits purine synthesis?

Answer 1

Trimethoprim

Question 2

Which drug is used in HIV therapy?

Answer 2

Saquinavir

Question 3

Which drug is used only in the treatment of urinary tract infections?

Answer 3

Nitrofuratoin

Question 4

Serious infections with MRSA require treatment with intravenous….

Answer 4

VANCOMYCIN

Question 5

Serious infections with gram negative organisms such as E.Coli should be treated with intravenous….

Answer 5

Gentamicin

Question 6

Serious fungal infections require treatment with intravenous:

Answer 6

Amphotericin B

Question 7

The pathogenesis of systemic Type lll hypersensitivity requires:

Answer 7

Immune complex formations

Question 8

Neutrophil polymorphs :

Answer 8

Are a major component of the acute inflammatory response

Question 9

Fibroblasts produce?

Answer 9

Collagen

Question 10

Histamine does what?

Answer 10

Relaxes vascular smooth muscle in acute inflammation

Question 11

Hypoxia causes what?

Answer 11

Reduced levels of tissue healing.

Question 12

Glyceryl trinitrate (GTN) is administered by the sublingual route to avoid:

Answer 12

First pass metabolism.

Question 13

A drug trial in which neither patient nor doctor is aware what treatment the patient is taking is called a:

Answer 13

Double blind trial

Question 14

A drug trial in which data is collected from case records after treatment is called a :

Answer 14

Retrospective trial

Question 15

A drug trial in which patients take both treatments being tested one after the other is called a :

Answer 15

Cross-over trial

Question 16

A drug trail in which pateints are allotted to treatment groups using random number generation is called a :

Answer 16

Randomised trial

Question 17

Name the major eukaryotic histones

Answer 17

H1 H2A H2B H3 H4

Question 18

How many chromosomes do you expect to label in each karyotype when using FISH to probe for X chromosomes in a Turner syndrome patient?

Answer 18

1- turner is X0

Question 19

what is the least suitable method of testing whether a healthy individual is a carrier for sickle cell anaemia?

Answer 19

Karyotyping

Question 20

Which mutation would you expect to have the least impact on the function of a gene with 1797 base pairs of coding sequence?

Answer 20

518+228C>T

Question 21

Mitosis:

Answer 21

Produces diploid cells from diploid cells.

Question 22

Meiosis:

Answer 22

Produces diploid cells from haploid cells.

Question 23

Fertilisation:

Answer 23

Produces diploid cells from haploid cells.

Question 24

The X chromosome:

Answer 24

Is transmitted by fathers to daughters but not to sons.

Question 25

The Y chromosome:

Answer 25

Is transmitted only by fathers.

Question 26

Retinoblastoma is caused by:

Answer 26

The loss of a tumour suppressor gene

Question 27

Leukaemia is a:

Answer 27

Malignant tumour of the white blood cells.

Question 28

A liposarcoma is a:

Answer 28

Malignant tumour of fatty tissue.

Question 29

A adenocarcinoma is a:

Answer 29

Malignant tumour of glandular epithelium.

Question 30

After any patient contact (physical or no) you should:

Answer 30

Wash your hands with plain soap and water.