Endocrine Formative Flashcards

1
Q

A patient with hypothyroidism would demonstrate which of the following symptoms?

  • Exopthalmos
  • Increased HR
  • Heat intolerance
  • Increased protein catabolism
  • Lethargy
A

Lethargy

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2
Q

Goitre is a common symptom of thyroid dysfunction, What pathology would it NOT be present in?

  • Primary hypothyroidism
  • Secondary hypothyroidism
  • Primary hyperthyroidism
  • Secondary hyperthyroidsim
  • Graves disease
A

Secondary hypothyroidism

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3
Q

a decrease in circulating cortisol levels would result in which of the following physiological responses?

  • Enhanced gluconeogenesis in liver?
  • Hypotension
  • Decreased ACTH secretion from the ant pit
  • Elevated levels of fatty acids in plasma
  • suppression of the immune system
A

-Hypotension

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4
Q

A person with primary hypercortisolism would demonstrate?

  • Depressed ACTH
  • Elevated CRH
  • Hypotension
  • Hypoglycaemia
  • Increased bone density
A

-Depressed ACTH

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5
Q

Chronic glucocorticoid therapy is associated with which of the following?

  • Enhanced cortisol release from the adrenal glands
  • Enhanced ACTH release from ant pit
  • Enhanced CRH release from the hypothalalmus
  • Adrenal insufficiency
  • Adrenal hypertrophy
A

Adrenal insufficiency

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6
Q

Which of the following will elevated free levels of calcium in plasma?

  • Alkalosis
  • Activation of oestoblasts
  • Increased phosphate excretion of the kidneys
  • Calcitonin
  • All of the above
A

-Increased phosphate excretion in the kidneys

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7
Q

Regarding GH which of the following is correct?

  • Its called somatostatin
  • Its called somatomedian
  • Its a steroid hormone
  • levels ins adults are at there highest during REM sleep
  • Its its relatively insignificant in terms of foetal and neonatal growth
A

D

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8
Q

Which of the following responses would ypu expect following insulin release?

  • hepatic gluconeogenesis
  • Increased ketone fromation
  • Increased uptake of glucose by the brain
  • Adipose lipolysis
  • Stimulation of Na=/K+ pase
A

Stimulation of Na/K+ ATPase

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9
Q

Which of the following is not a glucose counter regulatory hormone?

  • Thyroid hormone
  • Epinephrine
  • Glucagon
  • Cortisol
  • GH
A

-Thyroid hormone stimulates gluconeogenesis, the increase in blood glucose stimulates the release of insulin

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10
Q

A 53 y/o man has T2DM. he has loast 1 stone what is the next step for his management plan?

A

-Biguanide-Metformin

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11
Q

Which symptom below is NOT typical of hypoglycaemia?

  • Headache
  • Itch
  • poor concentration
  • Sweating
  • irritability
A

Itch

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12
Q

32 y/o patient with T1DM blood sugar is 3.2mmol/L and he tells you he is feeling well?

  • Adminster IM glucagon
  • Send him home for lunch
  • Give 200ml of Orange juice
  • Give a digestive biscuit
  • Administer his lunchtime insulin
A

-Give 200ml of OJ

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13
Q

23 y/o is diagnosed with hyperthyroidism and has been commenced on Carbimazole, what do you need to counsel him regarding?

A

-Neutropenia

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14
Q

All of the conditions below are well recognised causes of secondary diabetes except one. which is it?

  • Acromegaly
  • Haemochromatosis
  • Addisons disease
  • Cushings disease
  • Chronic Pancreatitis
A

-Acromegaly

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