PNS Pathology Flashcards
Glove and stocking pattern neuropathy
Diabetic neuropathy
Unilateral facial weakness
Bell’s palsy
Pain in the distribution of maxillary and mandibular branches of trigeminal
Trigeminal neuralgia
Down & out gaze
Occulomotor palsy
Neuropathy in digits 1-4.5 including palm
Carpal tunnel syndrome (median nerve)
Claw hand deformity
Ulnar nerve palsy
Neuropathy over upper, lateral thigh
Meralgia paresthetica (lateral femoral cutaneous nerve)
Classic ascending paralysis
Guillain-Barre Syndrome
Like GBS, but not usu autonomic/respiratory involvement
CIDP
Distal onset neuropathy with slow progression
Toxic neuropathy
Cranial nerve palsies, then flaccid paralysis
Botulism toxin
Distal, painful neuropathy
HIV-related
Cranial nerve neuropathies, especially BL facial nerve, spinal nerve radiculopathies
Lyme disease
Continuous burning dermatomal pain with paroxysmal lancinating pain
Postherpetic neuralgia
What viral DNA might you find in facial nerve specimens of patients with Bell’s palsy?
HSV1
What clinical finding is significant for advanced carpal tunnel syndrome? (looking beyond the paresthesia)
Thenar eminence atrophy
What clinical finding is significant for ulnar neuropathy?
Claw hand deformity
What is the special histo procedure and characteristic finding for herpes zoster?
Tzanck smear
Multinucleated giant cells
What disease is associated with Hutchinson’s sign?
Herpes zoster
Compare clinical findings of Neurofibromatosis type 1 and 2.
1: unilateral w/ cutaneous neurofibromas and cafe au lait spots
2: bilateral, leads to hearing loss before age 21
Histo findings of a neurofibroma
Spindle cells
