PNRC07 Flashcards
Two main complications of INO
Methemoglobinemia and Nitrogen Dioxide NO2
What can you do if the complications arise from INO?
decrease the Nitric
What are the levels that we are concerned with when it comes to MetHb and NO2
Need to wean if:
>5% methemoglobin
>5 ppm
Indications for weaning INO
hemodynamically stable on FIO2 <40% with Peep of 5 or less.
A pt that has ventilation problems can benefit from what
HELIOX
A pt that is having issues with oxygenation would benefit from what?
Nitric
Nitric Oxide enhances what vessels?
It will selectively produce pulm dilation.
**It will only dilate the blood vessels adjacent to functioning alveoli…NOT alveoli that is collapsed/fluid filled
Hyperoxygenating a pt who is ready to wean from INO
Set FiO2 to .6 to .7 OR 20% above before DCing the INO.
***This is done AFTER the INO has been reduced to lowest possible dose.
The FDA has approved INO tx for what ppl
Respiratory failure associated with pulmonary HTN and >34 weeks
OI formula
(Mean Airway Pressure x O2%) / PaO2
Why does INO work well with HFOV
Improves the response to INO by decreasing shunting
What likely causes methemoglobinemia vs Nitrogen Dioxide
Met Hb caused from high INO doses
NO2 caused from high PPMs and high FiO2
How to wean down INO
Reduce the INO to the lowest effective dose in increments of 50%. (10 to 5 to 2.5 ect)
What is the best attribute of Helium?
It has an extremely low density allowing it to decrease WOB, which is why it aids in ventilation NOT oxygenation.
Main indications for Heliox treatment
Upper airway obstruction (Foreign body aspiration) and Status asthmaticus.
How does heliox work?
It decreases Raw by creating more laminar flow and removes a much larger amount of CO2.
***DOES NOT treat the problem, only acts as a band-aid, this is called a temporizing agent
How do you deliver heliox if pt is not on ventilator?
non-rebreathing mask
**HAVE TO KEEP valves closed on the mask
Available ratios for heliox delivery
80/20 and 70/30
What patients receive 70/30 heliox?
Patients that are already on oxygen or pt that isnt on oxygen with an ABG showing hypoxia
**Think about it, 70/30 has more O2 in it than 80/20
Why do you need a special flow meter/regulator?
Because the flow meter will read a very false LOW
**Need to use conversions to calculate actual flow