PNEUMOCONIOSIS Flashcards

1
Q

DD for EGG SHELL CALCIFICATION
🌟A Silly Cool Sergeant Likes His Tubercular Blast

A

Amyloidosis
Silicosis
Coal worker pneumoconiosis
Lymphoma - hodgkins ( present 9-10 yr post radiotherapy )
Histoplasmosis
Tuberculosis
Blastomycosis

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2
Q

DD for Conglomerate masses

A

Silicosis
CWP
talcosis

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3
Q

MCC of Caplans syndrome

A

Silicosis

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4
Q

Most common pneumoconiosis

A

Silicosis

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5
Q

Most fibrogenic pneumoconiosis

A

Silicosis ( quartz)

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6
Q

Least fibrogenic pneumoconiosis

A

CWP

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7
Q

Most common pneumoconiosis associated with TB

A

Silicosis

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8
Q

Pneumoconiosis with least risk of developing lung cancer

A

CWP

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9
Q

Pneumoconiosis affecting Lower lung

A

Asbestosis

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10
Q

Pneumoconiosis affecting Lower lung

A

Silicosis
CWP
Berylliosis

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11
Q

Caplans syndrome

A

Rheumatoid arthiritis nodules ( in upper lung ) + pneumoconiosis ( mostly silicosis )

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12
Q

Most common type of lung cancer caused by pneumoconiosis

A

Non small cell carcinoma
( Adenocarcinoma)

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13
Q

Most common lung cancer caused in Asbestosis

A

Bronchogenic Cancer

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14
Q

Diagnosis of Silicosis

A

ACUTE :
Hilar LNAP
BAL- milky fluid , PAS + flocculent densities
HRCT - Crazy pavement appearance
Ground glass opacities with interstitial septal thickening along with interspersed normal areas

CHRONIC :
CXR- Egg shell calcification in upper lung (<1cm nodules )
- conglomerate masses

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15
Q

Cause of productive cough in acute silico proteinosis

A

Secondary alveolar proteinosis
Due to collection of Surfactants as a result decreased macrophage action ( because of exposure to silica dust )

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16
Q

Silica reaction

A

Formation of calcified fibrotic nodule in lung parenchyma which causes inflammatory reaction leading to PMF in later stages

17
Q

Silicosis increases risk of

A

TB
COPD
LUNG CANCER
COR PULMONALE
CAPLANS SYNDROME

18
Q

Erasmus syndrome

A

Systemic sclerosis after exposure to SILICA

19
Q

Comet tail sign

A

HRCT finding
Seen in Rounded atelectasis / folded lung syndrome / Blesovsky syndrome

Diffuse pleural thickening pulls bronchoalveolar bundles thus producing sign

Rare complication of Asbestosis

Intense pleural reaction causing folding of lung and pleura

20
Q

Virus ass with mesothelioma

A

Simian virus 40

21
Q

IOC for Asbestosis

A

Thoracoscopy guided biopsy

22
Q

Most specific cancer in Asbestosis

A

Mesothelioma

23
Q

Most common lung cancer in Asbestosis

A

Non small cell lung cancer ( adenocarcinoma)

24
Q

Ferrugineous bodies or asbestos bodies , other name

A

Asbestos fibres covered with FERRITIN
Golden beaded appearance on HPE

25
Q

Plaques in Asbestosis ( benign )

A

Discrete : Clover leaf appearance
Masses: candle dripping appearance

26
Q

Extra pulmonary cancers due to Asbestosis

A

Stomach cancer
Laryngeal ca
Colon ca

27
Q

Types of asbestos fibres (6)

A

Chrysolite
Crocidolite
Amosite
Anthophyllite
Tremolite
Actinolite

28
Q

Mgt of mesothelioma

A

Pemetrexate + cisplatin
⬇️
Nor response
⬇️
Gemcitabine ( anti metabolite )