PMHNP Certificate Study Addiction Flashcards

1
Q

Addiction is believed to be the result of an entrenched neuronal system of chemical rewards caused by the release of

A

dopamine into the ventral tegmental area (VTA)

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2
Q

Persistent and increased use of a substance or behavior that, when discontinued, causes distress and an urge to resume use despite related adverse consequences; sometimes known as psychological dependence

A

Addiction

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3
Q

Repeated use of a substance for physical needs leading to increased tolerance, and, when discontinued, results in physical withdrawal symptoms.

A

Dependence

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4
Q

The use of any substance that deviates from approved social or medical practice.

A

Abuse

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5
Q

The learned behavior pattern characterized by enabling maladaptive coping motivated by fear of losing the relationship. Usually seen in the family members of an identified patient.

A

Codependence

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6
Q

The physiological process caused by a physical change in the body due to repeated exposure to a substance.

A

Neuroadaptation

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7
Q

The process by which one drug can be substituted for another drug producing the same physiological and psychological effect (e.g., benzodiazepine and phenobarbital).

A

Cross Tolerance

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8
Q

A substance-specific cluster of signs and symptoms that occurs when reducing or stopping the consistent use of the substance.

A

Withdrawal

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9
Q

The condition in which repeated administration of a dosage causes a decreased effect despite increasingly larger doses, which are required to obtain the effect observed of the original dosage.

A

Tolerance

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10
Q

The co-occurrence of a substance use disorder with a primary mood disorder.

A

Dual Diagnosis

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11
Q

Substance use disorder requires how many DSM V symptoms over how much time?

A

2 or more over 12 months

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12
Q

How is substance abuse positively reinforced?

A

dopamine mediated in the ventral tegmental area and nucleus accumbens in the brain.

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13
Q

How is substance abuse negatively reinforced

A

When they stop using it; GABA mediated response triggers symptoms of dysphoria and anxiety

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14
Q

Agitation, restlessness, irritability, grandiosity, elatedness, euphoria, aggression, lability may indicate use of

A

stimulants

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15
Q

Dysphoria, impaired attention, impaired memory, disinhibition, psychomotor retardation, paranoia may indicate use of

A

Depressants

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16
Q

Mood swings, panic, aggression, paranoia, flashbacks, tremors, impaired cognition may indicate use of

A

Hallocinagens

17
Q

Paranoia, confusion, disorientation to time may indicate use of

A

Cannabis

18
Q

Irritability, delirium, confusion, stupor may indicate use of

A

inhalants

19
Q

Pinpoint pupils and or nystagmus indicate

A

Opioid use

20
Q

What labs will likely be elevated with alcohol abuse?

A

AST, ALT, GGT, PT, Potassium, Cholesterol, Triglycerides, Amylase, Homocysteine

21
Q

Would lab will likely be decreased with alcohol abuse?

A

sodium

22
Q

What is legal intoxication of blood alcohol level?

A

0.08%

23
Q

What is considered an impaired blood alcohol level?

A

0.08-0.4%

24
Q

At what blood alcohol level is there a risk of death?

A

> 0.4%

25
Q

Which type of withdrawals can be fatal?

A

Benzodiazepines and alcohol

26
Q

should not be used until the patient has been alcohol free for at least 12 hours. The client should avoid any alcohol-containing products (mouthwash, cough medicine, vinegar, extracts) for up to 14 days after the last dose.

A

Disulfiram (Anatabuse)

27
Q

Which medication Reverses opioid sedation?

A

Naloxone

28
Q

Which medication is longer acting, reduces cravings, enhances abstinence efforts by blocking reward associated with substance?

A

Naltrexone

29
Q

Which medication reduces opioid cravings, facilitates opioid detox, preferred for long-acting formulations

A

Buprenorphine

30
Q

Which medication reduces cravings, facilitates opioid detox, preferred for short acting formulations

A

Buprenorphine/ naloxone

31
Q

Which medication is long-acting opioid suppresses withdrawal, requires a government approved program

A

methadone

32
Q

Which medication reduces alcohol cravings and promotes abstinence-reducing tolerance effects

A

Acamprosate

33
Q

Which medication is aversive therapy when alcohol is consumed: vomiting, nausea, headache, flushing

A

Disulfiram

34
Q

Which two antidepressants can be prescribed for substance use disorder?

A

citalopram and bupropion

35
Q

Which Selective serotonin (5-HT3) antagonist can be prescribed to reduce cravings?

A

Ondansetron

36
Q

The patient’s reaction to a lapse, if attributed to self-failure; negative emotions may follow. Alternatively, if the lapse is viewed as a learning opportunity relapse is less likely to occur and the likelihood of future relapse is reduced.

A

Abstinence violation effect

37
Q

When is the most common time for drug and alcohol debut?

A

Adolesence

38
Q

In the older adult with substance use disorder you may opt for what treatment over detox?

A

harm reduction strategy rather than total abstinence given the physiological strain of detox; requires