(PM3B) Anxiety Disorders Flashcards
What is anxiety?
Prolonged or exaggerated response
To a real or imagined threat
Interferes with normal life
Cannot be attributed to any known neurological or organic dysfunction
What percentage of the population have anxiety?
~15%
Is long-term drug treatment for anxiety recommended?
No
Which molecules in the blood mediate anxiety?
(1) Serotonin
(2) Noradrenaline
(3) Dopamine
(4) GABA
What are some psychiatric symptoms of anxiety?
(1) Fear/ tension/ apprehension/ panic/ terror
(2) Hyper-arousal excitability + outbursts of hostility
(3) Insomnia
(4) Circling thoughts + lapses of memory
(5) Inability to concentrate + easily distracted
What are some somatic symptoms of anxiety?
(1) Cardiovascular: palpitations/ increased BP/ tachycardia/ bradycardia/ flushing/ pallor
(2) Respiratory: rapid shallow breathing (hyperventilation)/ breathlessness (dyspnoea)
(3) GI: diarrhoea/ dyspepsia/ dysphagia/ churning stomach
(4) Musculoskeletal: agitation/ restlessness/ tremor/ muscle tension
(5) Metabolic: high blood glucose/ high glucocorticoids
(6) Excessive sweating/ urge to defecate or urinate
What are some different types of anxiety disorder?
(1) Generalised anxiety disorder – GAD
(2) Obsessive Compulsive Disorder – OCD
(3) Post-traumatic Stress Disorder – PTSD
(4) Panic Disorder – PD
(5) Specific phobias
(6) Social phobias
Describe the aetiology of anxiety?
No evidence of pathology of anxiety
OCD may be partially due to disturbed circuits
Some evidence for a genetic factor in some anxiety disorders – e.g. OCD
What are the treatment aims for anxiety therapy?
(1) Discover + remove cause
(2) Assess severity of anxiety response
(3) Relieve distress
(4) Implement long-term measures to prevent recurrence
What are some of the common psychological treatments for anxiety?
(1) Counselling
(2) Cognitive Behavioural Therapy (CBT)
(3) Exposure therapy
(4) Mindfulness + relaxation therapy
What is the phramacological treatment for acute anxiety?
Benzodiazepines
e.g. lorazepam/ diazepam/ alprazolam
Fast-acting relief
What is the usual first line treatment for most anxiety disorders?
(1) SSRIs – selective serotonin reuptake inhibitors
Recommended for long-term therapy
When is pregabalin indicated for treatment?
(1) Epilepsy
(2) Generalised anxiety disorder – GAD
When are tricyclic antidepressants indicated for treatment?
(1) Obsessions
(2) Phobias
e.g. clomipramine
When is buspirones indicated for treatment?
(1) Generalised anxiety disorder – GAD
(2) Acute anxiety