Pleural effusion Flashcards
Pleural effusion presentation
Asymptomatic early
SOB +/- Chest pain
Reduced breath sounds, stony dull percussion and reduced chest expansion over affected area.
Types of Fluid in Plural space
Transudates- low protein fluid Exudates- high protein fluid Empyema- pus Haemothorax- blood Chylothorax-lymph
Investigations
CXR: >330ml visible on plain film. Obliterated costophrenic angle
Plural Aspirate: gross appearance, pH, protein and lactic dehydrogenase, C&S, cytology
Transudate vs Exudate
Transudate caused by low oncotic or high hydrostatic pressure.
Exudate cused by disruption of pleura itself causing increased production or decreased re-absorption of fluid.
Transudate < 30protein < Exudate
Transudate < 200 lactic dehydrogenase < Exudate
Causes Transudate
Heart Failure Nephrotic Syndrome Pericarditis Hypothyroidism Some Ca (Meigs syndrome, ovarian) Liver Cihhrosis
Causes Exudate
Pnuemonia Pulmonary Ca/ Mesothelioma TB Sarcoid Autoimmune Rheumatic disease (SLE, RA) Trauma PE Pancreatitis Post MI
Management Plural Effusion
Hx, Exam, CXR If likely Transudate- treat cause If not resolved or likely Exudate refer Respiratory Aspiration under US guidance Cause identified - treat cause Not identified CT thorax +/- Biopsy Drain if symptomatic Antibiotics if Empyema If recurrent Drain to dry then Pleurodesis with talc/tetracycline Surgery/ permanent drain if progressive