Pleural Effusion Flashcards

1
Q

What is a pleural effusion

A

A collection of fluid in the pleural space

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2
Q

What causes a pleural effusion

A

When the balance between fluid filtration by the parietal pleura and fluid absorption by the visceral pleura is no longer balanced, leading to a build up of fluid in the pleural space

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3
Q

What might a patient with pleural effusion complain of

A

Breathlessness - sometimes with pleuritic pain

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4
Q

Does pleural effusion cause clubbing

A

No

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5
Q

What would you expect to find on examination of a patient with a pleural effusion

A
Tachypnoea
Deviated trachea - away from effusion
Asymmetrical decreased chest expansion
Reduced tactile vocal fremitus
Stony dull to percussion
Reduced breath sounds
  • Bronchial breath sounds may be heard at the top of the effusion
  • Any signs of failure/malignancy that may indicate a cause
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6
Q

What is aegophony

A

Bronchial breathing at the top of an effusion

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7
Q

What diagnostic investigations would be done for a patient with a suspected pleural effusion

A

CXR

Pleural tap

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8
Q

What would you test the pleural tap for in a pleural effusion

A
Protein
Glucose
LDH
Cell count
Culture and microscopy
Cytology
pH
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9
Q

What information does the protein level in a pleural tap give you

A

Whether the effusion is a transudate or an exudate

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10
Q

What is a transudate

A

An effusion with a protein content less than 30

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11
Q

What is an exudate

A

An effusion with a protein content >30

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12
Q

How would transudates and exudates appear on a pleural tap

A

Yellow, straw colour

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13
Q

What information does the glucose in a pleural tap give you

A

Low glucose points towards infection or connective tissue disease as the cause of the effusion

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14
Q

What information would you get from the cell count in a pleural tap

A

Neutrophils - predominant cells in acute inflammation or infection
Lymphocytes - predominant cells in chronic effusions, particularly caused by TB or malignancy

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15
Q

What might cytology show on a pleural tap

A

Malignant cells

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16
Q

What might microbiology examination of pleural fluid show

A

May identify TB or bacterial infection

17
Q

What would bloodstained pleural fluid indicate

A

Malignancy
Pulmonary infarction
Severe inflammation

18
Q

What would pus in pleural fluid indicate

A

Empyema

19
Q

What would frank blood in pleural fluid indicate

A

Haemothorax

20
Q

How do you determine if the pleural fluid is a transudate or an exudate in cases where the protein level is borderline ie. 25-35

A

Lights Criteria

21
Q

What is Lights Criteria

A

Pleural fluid protein/Serum protein >0.5
Pleural fluid LDH/Serum LDH >0.6
Pleural fluid LDH > 2/3 upper limit of normal

If any one of these criteria is met, effusion is considered an exudate

22
Q

What are some causes of a transudate

A

3 Failures

  • Cardiac failure
  • Renal failure
  • Liver failure

Hypoalbuminaemia
Hypothyroidism

*Transudative effusions are commonly bilateral

23
Q

What are some causes of an exudate

A

MIII

Malignancy - metastatic carcinoma, mesothelioma
Infection - TB, empyema
Infarction - pulmonary infarction
Inflammation - SLE, RA, benign asbestos effusion

  • Exudates results from increased permeability of the pleura associated with pleural disease
  • Exudates are usually unilateral
24
Q

What is Meig’s syndrome

A

A rare cause of transudative pleural effusion

Benign ovarian pathology
Ascites
Right sided pleural effusion

25
Q

Which cancers most commonly metastasise to the pleura

A
Lung
Breast
Ovarian
GI
Lymphoma
26
Q

How would you manage a pleural effusion

A

Treat the underlying cause

Therapeutic thoracocentesis

27
Q

What are the complications of therapeutic thoracocentesis

A

Pneumothorax following the procedure

Re-expansion pulmonary oedema

28
Q

What is an empyema

A

Collection of pus within the pleural cavity
Most commonly as a complication of pneumonia
Exudate with decreased glucose and pH

29
Q

How do you treat an empyema

A

Prolonged antibiotic therapy

Drainage of the pus

30
Q

What condition is empyema particularly associated with

A

Aspiration pneumonia

31
Q

What complication can occur if an empyema remains untreated

A

It can lead to a thick pleural peel which restricts lung expansion
Requiring surgical decortication