COPD Flashcards

1
Q

What is COPD

A

A disease characterised by airflow obstruction which is usually progressive and irreversible. It encompasses emphysema and chronic bronchitis

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2
Q

How is obstruction defined diagnostically in respiratory disease

A

FEV1 less than 80% and FEV1/FVC ratio less than 0.7

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3
Q

How do you diagnose bronchitis

A

It is a symptomatic diagnosis - sputum production for >3 months of the year, for >1 year

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4
Q

How do you diagnose emphysema

A

It is a histological diagnosis, dilatation of the air spaces distal to the terminal bronchioles

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5
Q

What are the causes of COPD

A
Smoking
Atmospheric pollution (most common worldwide) - may play a role
Alpha-1 Antitrypsin deficiency - a rare cause of emphysema
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6
Q

What might a patient with COPD complain of

A

SOB
Cough with sputum
Wheeze

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7
Q

Does COPD cause clubbing

A

No

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8
Q

What signs might you see on a COPD patient

A
Use of accessory muscles
Pursed lip breathing
Asterixis - if CO2 retention
Reduced cricosternal distance - hyperexpansion
Reduced chest expansion
Reduced breath sounds

*May be coarse crackles if infective exacerbation

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9
Q

Why might you do an ECG on a COPD patient

A

To look for signs of right ventricular hypertrophy

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10
Q

What oxygen saturations are you aiming for in an acutely ill COPD patient

A

88-92%

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11
Q

How would you give oxygen in the acute setting to a COPD patient

A

Use either a 24% or 28% venturi mask and oxygen at 4L/min

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12
Q

What is the criteria for long term oxygen therapy for a COPD patient

A

If PaO2 less than 7.3 and patient is stable (more than 5 weeks since last exacerbation)

Non-smoker (long term)

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13
Q

What important investigations should be done to investigate COPD?

A

Bedside- culture MCS

ABG

Imaging: CXR- hyperexpansion, bullae, ruling out malignancy, infective exacerbation or other lung disease

Pulmonary function tests

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14
Q

What is the medical management for chronic COPD?

A

3 steps:

  1. Relievers- short acting beta agonists e.g Atrovent
  2. LABA e.g. Spiriva/long acting muscarinic antagonist
  3. Combination with steroids e.g. Seretide
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15
Q

Why are steroids avoided where possible in Copd?

A

Expensive

Increased risk pneumonia

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16
Q

What is the management of an acute exacerbation of COPD?

A

Controlled O2 therapy

Nebulised bronchodilators

Steroids: IV hydrocortisone, followed by 7-14 days oral prednisolone

Abx: doxycycline

NIV: if no response and severe hypercapnic respiratory failure: pH less than 7.35

Aminophylline IV- if no response

17
Q

What are the most common causative pathogens for an acute infective exacerbation of COPD?

A

Strep pneumonia
Haemophilus influenza
Moraxella cattarhalis