PLE 2019 Flashcards

1
Q

How can infant’s perception and cognition be demonstrated during the first months of life? Demonstrated by:

A. Crying when hungry or sleepy
B. Eye gazing, head turning and sucking
C. Smiling when approached by mom or dad
D. Waking up during feeding period

A

A. Crying when hungry or sleepy

Social and Emotional:
● Begins to smile at people
● Can briefly calm herself (may bring hands to mouth and suck on hand)
● Tries to look at parent

Language/Communication
● Coos, makes gurgling sounds
● Turns head toward sounds

Cognitive (learning, thinking, problem-solving)
● Pays attention to faces
● Begins to follow things with eyes and recognize people at a distance
● Begins to act bored (cries, fussy) if activity doesn’t change

Movement/Physical Development
● Can hold head up and begins to push up when lying on tummy
● Makes smoother movements with arms and legs

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2
Q

During early childhood, children should sleep for how long without interruption?

A. 12-16 hours
B. 11-13 hours
C. 8-10 hours
D. 5-7 hours

A

C. 8-10 hours

> Toddler (1-3 yr)
Total sleep: average is 11-13 hr
Nighttime: average is 9.5-10.5 hr
Naps: average is 2-3 hr; decrease from 2 naps to 1 at average age of 18 mo

> Preschool (3-5 yr)
Nighttime: average is 9-10 hr
Naps decrease from 1 nap to no nap
Overall, 26% of 4 yr olds and just 15% of 5 yr olds nap

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3
Q

Baby Nicole already knows how to play peek-a-boo. She copies sounds and movements of others and points at things. She is able to stand with support, crawl and get into sitting position without support, and pulls to stand. She has met the milestones of what age?

A. 4 months
B. 9 months
C. 6 months
D. 12 months

A

B. 9 months

> 9 months
● May be afraid of strangers
● May be clingy with familiar adults
● Has favorite toys
● Understands “no”
● Makes a lot of different sounds like “mamamama” and “bababababa”
● Copies sounds and gestures of others
● Uses fingers to point at things
● Watches the path of something as it falls
● Looks for things she sees you hide
● Plays peek-a-boo
● Puts things in his mouth
● Moves things smoothly from one hand to the other
● Picks up things like cereal o’s between thumb and index finger
● Stands, holding on
● Can get into sitting position
● Sits without support
● Pulls to stand
● Crawls

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4
Q

The 9th month physical examination of an infant is difficult to do. Which endeavor is the LEAST likely way to get the child’s cooperation?

A. Talk to parent avoiding direct eye contact with child
B. Examine the child while on parent’s lap
C. Talk to the child with direct eye contact
D. Introduce the child to a small washable toy

A

A. Talk to parent avoiding direct eye contact with child

> General guidelines:
● Approach the infant gradually, using a toy or object for distraction.
● Perform much of the examination with the infant in the parent’s lap.
● Speak softly to the infant or mimic the infant’s sounds to attract attention.
● If the infant is cranky, make sure he or she is well fed before proceeding.
● Ask a parent about the infant’s strengths to elicit useful developmental and parenting information.
● Don’t expect to do a head-to-toe exam in a specific order. Take what the infant gives you and save the mouth and ear exam for last

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5
Q

What is/are the cause/causes of digital clubbing?

A. Chronic cardiac failure
B. Acute respiratory insufficiency
C. Defective heart valves
D. Chronic hypoxia and chronic lung disease

A

A. Chronic cardiac failure

> An increase in hypoxia may activate local vasodilators, consequently increasing blood flow to the distal portion of the digits; however, in most cases, hypoxia is absent in the presence of clubbing, and many diseases with noted hypoxia are not associated with clubbing.

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6
Q

Which statement is FALSE with regards to the origin of chronic coughs?

A. Lower respiratory stimuli include excessive secretions, aspirated foreign material, inhaled dust/gases.
B. Origin of coughs can also be a response to infectious agents or cigarette smoke.
C. Nighttime cough suggests upper airway disease such as sinusitis.
D. The receptors of chronic coughs are mostly located in the lower respiratory tract.

A

D. The receptors of chronic coughs are mostly located in the lower respiratory tract.

> Cough is a reflex response of the lower respiratory tract to stimulation of irritant or cough receptors in the airways’ mucosa. The most common cause in children is airway reactivity (asthma). Because cough receptors also reside in the pharynx, paranasal sinuses, stomach, and external auditory canal, the source of a persistent cough may need to be sought beyond the lungs.
Specific lower respiratory stimuli include excessive secretions, aspirated foreign material, inhaled dust particles or noxious gases, cold or dry air, and an inflammatory response to infectious agents or allergic processes.
Posterior pharyngeal drainage combined with a nighttime cough suggests chronic upper airway disease such as sinusitis. Additional useful information can include a history of atopic conditions (asthma, eczema, urticaria, allergic rhinitis), a seasonal or environmental variation
in frequency or intensity of cough, and a strong family history of atopic conditions, all suggesting an allergic cause; symptoms of malabsorption or family history indicating cystic fibrosis; symptoms related to feeding, suggesting aspiration or gastroesophageal reflux; a choking episode, suggesting foreign-body aspiration; headache or facial edema associated with sinusitis; and a smoking history in older children and adolescents or the presence of a smoker in the house.

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7
Q

Which one occurs during normal cardiac development?

A. The aortic sac gives rise to the right and left 1st aortic arches.
B. The 1st and 2nd arches form the common and internal carotid arteries.
C. The paired dorsal aorta will fuse to form the descending aorta.
D. The 5th arch persists in the mature circulation as a segment of the aortic arch.

A

C. The paired dorsal aorta will fuse to form the descending aorta.

> The aortic arch, head and neck vessels, proximal pulmonary arteries, and ductus arteriosus develop from the aortic sac, arterial arches, and dorsal aortae. When the straight heart tube develops, the distal outflow portion bifurcates into the right and left 1st aortic arches, which join
the paired dorsal aortae. The dorsal aortae will fuse to form the descending aorta.
The proximal aorta from the aortic valve to the left carotid artery arises from the aortic sac.
The 1st and 2nd arches largely regress by about 22 days, with the 1st aortic arch giving rise to the maxillary artery and the 2nd to the stapedial and hyoid arteries. The 3rd arches participate in the formation of the innominate artery and the common and internal carotid arteries. The right 4th arch gives rise to the innominate and right subclavian arteries, and the left 4th arch participates in formation of the segment of the aortic arch between the left carotid artery and the ductus arteriosus.
The 5th arch does not persist as a major structure in the mature circulation. The 6th arches join the more distal pulmonary arteries, with the right 6th arch giving rise to a portion of the proximal right pulmonary artery and the left 6th arch giving rise to the ductus arteriosus. The aortic arch between the ductus arteriosus and the left subclavian artery is derived from the left-sided dorsal aorta, whereas the aortic arch distal to the left subclavian artery is derived from the fused right and left dorsal aortae. Abnormalities in development of the paired aortic arches are responsible for right aortic arch, double aortic arch, and vascularrings.

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8
Q

Prostaglandin may be administered to patient with patent ductus arteriosus in which situation?

A. Patients who cannot undergo surgical management of ventricular septal defect.
B. Patient waiting for surgical management of transposition of great arteries.
C. Ductus arteriosus of a full term baby which has not closed a week after birth.
D. Ductus arteriosus persists in a child who is already 3 years old.

A

B. Patient waiting for surgical management of transposition of great arteries.

> Before birth, oxygenation of the fetus with transposition of great arteries is only slightly abnormal, but after birth, once the ductus arteriosus begins to close, the minimal mixing of systemic and pulmonary blood via the patent foramen ovale is usually insufficient and severe hypoxemia ensues, generally within the 1st few days of life.
When transposition is suspected, an infusion of prostaglandin E1 should be initiated immediately to maintain patency of the ductus arteriosus and improve oxygenation (dosage: 0.01-0.20 μg/kg/min).

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9
Q

Which of the following statements is true regarding cyanosis in the pediatric age group?

A. Acrocyanosis is a symptom of worsening cardiac functions in a newborn
B. Turning blue around the lips after crying vigorously is a definitive sign of heart disease
C. Cyanosis at rest is often overlooked due to variations in skin color of children
D. Mucous membranes are spared or not involved in true cyanosis in newborns

A

C. Cyanosis at rest is often overlooked due to variations in skin color of children

> Many infants and toddlers turn “blue around the lips” when crying vigorously or during breath- holding spells; this condition must be carefully differentiated from cyanotic heart disease by inquiring about inciting factors, the length of episodes, and whether the tongue and mucous membranes also appear cyanotic.
Newborns often have cyanosis of their extremities (acrocyanosis) when undressed and cold; this response to cold must be carefully differentiated from true cyanosis, where the mucous membranes are also blue.

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10
Q

What are heart murmurs?

A. They are signs of leaflet prolapse radiating anteriorly
B. They are results of audible vibrations caused by increased turbulence timed within the cardiac cycle
C. They are the differences between two cardiac chambers, ventricles and arteries
D. They are progressive attenuations of left ventricle to left atrial pressure gradient

A

B. They are results of audible vibrations caused by increased turbulence timed within the cardiac cycle

> Cardiac murmur is a characteristic sound generated by turbulence of blood flow through an orifice of the heart.

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11
Q

Which congenital malformation syndrome is least associated with the development of ventricular septal defect?

A. Trisomy 13
B. Fetal alcohol syndrome
C. Down’s syndrome
D. Congenital rubella

A

D. Congenital rubella

> Trisomy 13 (T13) and 18 (T18) are frequently (up to 80%) associated with multiple anomalies including congenital heart defects (CHD) such as atrial or ventricular septal defects (ASD, VSD), patent ductus arteriosus (PDA), atrioventricular septal defect (AVSD), tetralogy of Fallot (TOF) and others.
The specific defects that have been observed from prenatal alcohol exposure include defects to the atrioventricular valves (tricuspid and mitral) that allow blood to flow backward into the atria; ventricular septal defects, commonly known as a “hole in the heart” between the left and right ventricles; enlargement of the left ventricle, the primary pumping chamber in the heart; and an increased risk of developing heart disease later in adult life.
Ventricular septal defect is a common cardiac anomaly in Down syndrome.
Congenital rubella may also present with VSD. However, the most common congenital heart defect associated is PDA.

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12
Q

A patient presents with VSD in which blood is shunted from right to left secondary to the development of pulmonary vascular disease. This condition is known as:

A. Pulmonary arteriovenous fistula
B. Eisenmenger syndrome
C. Ectopia cordis
D. Ebstein anomaly

A

B. Eisenmenger syndrome

> Eisenmenger syndrome (ES) is a constellation of symptoms that arise from a congenital heart defect and result in large anatomic shunts. Due to anatomic variations present at birth, hemodynamic forces initially result in a left-right shunt, which develops into severe pulmonary arterial hypertension (PAH) and elevated vascular resistance. Ultimately, due to increased pulmonary vascular resistance, the left-to-right shunt will become a right-to-left shunt, resulting in significant hypoxemia and cyanosis.

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13
Q

The boot shaped sign seen in the radiographs of patients with Tetralogy of Fallot is from:

A. The convergence behind the heart of the pulmonary vein, instead of draining into the left atrium
B. The shortening of the left ventricular inflow tract and elongation of the left ventricular outflow tract
C. The contour of the aorta deformed by both pre and post stenotic dilation, and dilation of the subclavian artery
D. The upturning of the cardiac apex due to right ventricular hypertrophy and by the concavity of the main pulmonary artery

A

D. The upturning of the cardiac apex due to right ventricular hypertrophy and by the concavity of the main pulmonary artery

> The boot-shaped heart sign is a conventional radiographic finding in patients with TOF. The toe of the boot is formed by the upward pointing cardiac apex, which makes an acute angle with the diaphragm. The upturned cardiac apex is ascribed to right ventricular hypertrophy and occurs in 65% of patients with TOF.

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14
Q

This type of total anomalous pulmonary venous return involves pulmonary venous connection at the cardiac level. The pulmonary veins join either the coronary sinus or the right atrium. What type is this?

A. Type IV TAPVR
B. Type I TAPVR
C. Type II TAPVR
D. Type III TAPVR

A

C. Type II TAPVR

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15
Q

The most common major congenital heart lesion is:

A. TOF
B. VSD
C. PDA
D. ASD

A

B. VSD

> VSD is the most common cardiac malformation and accounts for 25% of congenital heart disease. Defects may occur in any portion of the ventricular septum, but most are of the membranous type.

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16
Q

Which is not a component of the four main defects in Tetralogy of Fallot?

A. VSD
B. LVH
C. Overriding aorta
D. Pulmonary stenosis

A

B. LVH

> The four components that make up the “tetralogy” include:

● a ventricular septal defect (VSD);
● pulmonary stenosis (subvalvar, valvar and/or supravalvar);
● an overriding aorta; and.
● right ventricular hypertrophy

17
Q

Which of the following correctly describes the flow of CSF in children?

A. Choroid plexus → lateral ventricle → aqueduct of sylvius → third ventricle → foramen of monroe → fourth ventricle
B. Choroid plexus → lateral ventricle → foramen of magendie → third ventricle → aqueduct of sylvius → fourth ventricle
C. Choroid plexus → lateral ventricle → foramen of monroe → third ventricle → aqueduct of sylvius → fourth ventricle
D. Choroid plexus → lateral ventricle → foramen of luschka → third ventricle → foramen of magendie → fourth ventricle

A

C. Choroid plexus → lateral ventricle → foramen of monroe → third ventricle → aqueduct of sylvius → fourth ventricle

> The ventricles are four fluid-filled cavities located within the brain; these are the two lateral ventricles, the third ventricle, and the fourth ventricle (Fig. 16-1). The two lateral ventricles communicate through the interventricular foramina (of Monro) with the third ventricle. The third ventricle is connected to the fourth ventricle by the narrow cerebral aqueduct (aqueduct of Sylvius). The fourth ventricle, in turn, is continuous with the narrow central canal of the spinal cord and,through the three foramina in its roof, with the subarachnoid space. The central canal in the spinal cord has a small dilatation at its inferior end, referred to as the terminal ventricle (Fig. 16-1).

18
Q

Which of the following should a 1 year old child be able to do?

A. Go up the stairs one step at a time
B. Can say two - word phrases
C. Throw objects
D. Makes a tower of two blocks

A

C. Throw objects

19
Q

A 5 year old child comes into your clinic due to fever from a respiratory tract infection. While doing your exam, he develops a 10-second episode of generalized seizure. Which of the following is the MOST likely diagnosis?

A. Benign rolandic epilepsy
B. Infantile spasms
C. Febrile seizure
D. Lennox - gastaut syndrome

A

C. Febrile seizure

> Febrile seizures are seizures that occur between the age of 6 and 60 mo with a temperature of 38°C (100.4°F) or higher, that are not the result of central nervous system infection or any metabolic imbalance, and that occur in the absence of a history of prior afebrile seizures.
A simple febrile seizure is a primary, generalized, usually tonic–clonic, attack associated with fever, lasting for a maximum of 15 min, and not recurrent within a 24-hr period.
A complex febrile seizure is more prolonged (>15 min), is focal, and/or reoccurs within 24 hr. Febrile status epilepticus is a febrile seizure lasting longer than 30

20
Q

The sleep-wake pattern is well developed at term. Alertness of the neonate depends on the following factors. Which of the following is LEAST contributory?

A. Gestational age
B. Presence of television
C. Time of last feeding
D. Room temperature

A

B. Presence of television

> Sleep–wake patterns are well developed at term. Because the level of alertness of a neonate depends on many factors, including the time of the last feeding, room temperature, and gestational age, serial examinations are critical when evaluating for changes in neurologic function.

21
Q

A child presents with cafe au lait spots, axillary freckling, ‘ballotable’ nodules, and elevated lumps in the skin. Which does this child MOST likely have?

A. Von - Hippel Lindau disease
B. Neurofibromatosis I
C. Neurofibromatosis II
D. Sturge Weber Disease

A

B. Neurofibromatosis I

> Neurofibromatoses are autosomal dominant disorders that cause tumors to grow on nerves and result in other abnormalities such as skin changes and bone deformities.
NF-1 is the most prevalent type, with an incidence of 1 in 3,000 live births, and is caused by dominant loss-of- function mutations in the NF-1 gene. The disease is clinically diagnosed when any 2 of the following 7 features are present:
(1) six or more café-au-lait macules larger than 5 mm in greatest diameter in prepubertal individuals and larger than 15 mm in greatest diameter in postpubertal individuals. Café-au-lait spots are the hallmark of neurofibromatosis and are present in almost 100% of patients.
(2) Axillary or inguinal freckling consisting of multiple hyperpigmented areas 2-3 mm in diameter. The frequency of axillary and inguinal freckling is reported to be >80% by 6 yr of age.
(3) Two or more iris Lisch nodules. Lisch nodules are hamartomas located within the iris and are best identified by a slit-lamp examination. They are present in more than 74% of patients withNF-1 but are not a characteristic of NF-2.
(4) Two or more neurofibromas or 1 plexiform neurofibroma. They are usually small, rubbery lesions with a slight purplish discoloration of the overlying skin.
(5) A distinctive osseous lesion such as sphenoid dysplasia (which may cause pulsating exophthalmos) or cortical thinning of long bones with or without pseudoarthrosis (e.g., tibia).
(6) Optic gliomas are present in approximately 15% of patients with NF-1 and represent mostly low-grade astrocytomas. They are the main central nervous system tumor with a marked increased frequency in NF-1.
(7) A 1st-degree relative with NF-1 whose diagnosis was based on the aforementioned criteria.

22
Q

Which of the following statements may NOT be true?

A. A large head is associated with a large brain
B. Flattening of the skull will need extensive investigation
C. If the brain is not growing, the skull will not grow
D. Head size may be increased secondary to hydrocephalus

A

B. Flattening of the skull will need extensive investigation

> If the brain is not growing, the skull will not grow; therefore, a small head frequently reflects a small brain, or microcephaly. Conversely, a large head may be associated with a large brain, or macrocephaly, which is most commonly familial but may be from a disturbance of growth, neurocutaneous disorder (e.g., neurofibromatosis), chromosomal defect (e.g., Klinefelter syndrome), or storage disorder.
Alternatively, the head size may be increased secondary to hydrocephalus or chronic subdural hemorrhages. Plagiocephaly, or flattening of the skull, can be seen in normal infants but may be particularly prominent in hypotonic or weak infants, who are less mobile.

23
Q

During examination of a 3 month old infant, you test his CNS by stroking the lateral surface of the sole. His big toe then dorsiflexes and the other toes fan out. This demonstrates which reflex?

A. Startle
B. Rooting
C. Moro
D. Babinski

A

D. Babinski

> Babinski sign occurs when stimulation of lateral plantar aspect of the foot leads to extension (dorsiflexion or upward movement) of the big toe (hallux). Also, there may be fanning of the other toes. This suggests that there has been spread of the sensory input beyond the S1 myotome to L4 and L5. An intact CST prevents such spread. In infants with at CST which is not fully myelinated, the presence of a Babinski sign in the absence of other neurological deficits is considered normal up to 24 months of age.
The Moro or startle reflex is elicited by supporting the infant in a semi erect position and then allowing the infant’s head to fall backwards onto the examiner’s hand. A normal response consists of symmetric extension and abduction of the fingers and upper extremities, followed by flexion of the upper extremities and an audible cry. An asymmetric response can signify a fractured clavicle, brachial plexus injury, or hemiparesis.
Rooting reflex is elicited by stroking the perioral skin at the corners of the mouth.The mouth will open and the infant will turn the head toward the stimulated side and suck.

24
Q

Which will NOT give a positive GUAIAC test in stools?

A. Nasal/oropharyngeal bleeding
B. Red dyes in food or drinks
C. Blood loss from GI tract
D. Maternal blood ingested

A

B. Red dyes in food or drinks

> Blood loss from the gastrointestinal tract is never normal, but swallowed blood may be misinterpreted as gastrointestinal bleeding. Maternal blood may be ingested at the time of birth or later by a nursing infant if there is bleeding near the mother’s nipple. Nasal or oropharyngeal bleeding is occasionally mistaken for gastrointestinal bleeding. Red dyes in foods or drinks can turn the stool red but do not produce a positive test result for occult blood.

25
Q

Where is the location of our “hunger and satiety centers?

A. Medulla
B. Hypothalamus
C. Cerebral cortex
D. Amygdala

A

B. Hypothalamus

> The Hypothalamus Contains Hunger and Satiety Centers:
Several neuronal centers of the hypothalamus participate in the control of food intake. The lateral nuclei of the hypothalamus serve as a feeding center, and stimulation of this area causes an animal to eat voraciously (hyperphagia). Conversely, destruction of the lateral hypothalamus causes lack of desire for food and progressive inanition, a condition characterized by marked weight loss, muscle weakness, and decreased metabolism. The lateral hypothalamic feeding center operates by exciting the motor drives to search for food.

26
Q

Why do infants need to be “burped” after feeding?

A. Infants feel full after feeding, burp to prevent vomiting
B. Infants feel comfortable after burping especially if they had full feeding
C. Infants swallow air during feeding, burp to prevent abdominal distention
D. Have to place infants upright position to prevent food regurgitation
C. Infants swallow air during feeding, burp to prevent abdominal distention
Gastrointestinal function varies with maturity; what is a
physiologic event in a newborn or infant might be a
pathologic symptom at an older age. A fetus can
swallow amniotic fluid as early as 12 wk of gestation,
but nutritive sucking in neonates first develops at about
34 wk of gestation. The coordinated oral and
pharyngeal movements necessary for swallowing
solids develop within the 1st few mo of life. Before this
time, the tongue thrust is upward and outward to
express milk from the nipple, instead of a backward
motion, which propels solids toward the esophageal
inlet. By 1 mo of age, infants appear to show
preferences for sweet and salty foods. Infants’ interest
in solids increases at approximately 4 mo of age. The
recommendation to begin solids at 6 mo of age is
based on nutritional and cultural concepts rather than
maturation of the swallowing process. Infants swallow
air during feeding, and burping is encouraged to
prevent gaseous distention of the stomach.

A