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Hematology 2 (Lecture) > Platelet Structure (P) > Flashcards

Platelet Structure (P) Flashcards

1
Q

What is the meaning of PLT?

A

Platelet

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2
Q

What are the characteristics of PLT?

A

1) Non-nucleated blood cells
2) Average diameter: 2.5 μm
3) For Wright-stained smears: PLT appearance is circular to irregular, lavender and granular

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3
Q

What is the normal mean PLT volume or MPV?

A

8-10 fL

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4
Q

What is the meaning of MPV?

A

Mean Platelet Volume

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5
Q

What is the normal peripheral blood PLT count?

A

150-400 x 10^9/L or 150,000-400,000 cells/mm^3

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6
Q

What is the average distribution of PLTs throughout RBC monolayer?

A

7-21 cells per 100x field

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7
Q

Is the volume of PLTs greater than men compared to women?

A

No, PLT volume is greater for women compared to men

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8
Q

Is the volume of PLTs greater than individuals with the age of 65 yo onwards?

A

No, PLT volume is greater for individuals with the age of 64 yo and below compared to individuals with the age of 65 yo onwards

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9
Q

What are the different types of PLTs?

A

1) Sequestered Platelets
2) Circulating Platelets
3) Reticulated or Stress Platelets

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10
Q

What is the population of sequestered PLTs?

A

It comprises one-third of total body PLTs

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11
Q

Where do sequestered PLTs happen (or occur)?

A

In the spleen

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12
Q

What is the population of circulating PLTs?

A

It comprises two-thirds of total body PLTs

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13
Q

What are circulating PLTs?

A

PLTs that are flowing in circulation

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14
Q

What are the 2 types of circulating PLTs?

A

1) Resting platelets

2) Collected blood platelets

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15
Q

What is the characteristic of resting PLTs?

A

These are biconvex

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16
Q

What is the characteristic of collected blood PLTs?

A

These are round up

17
Q

What is the characteristic of reticulated or stress platelets (in terms of size)?

A

Has an average diameter of 6 μm

18
Q

What is the effect of having reticulated or stress PLTs?

A

Increased MPV of 12-14 fL

19
Q

What is the characteristic (of reticulated or stress PLTs) in EDTA WB?

A

These are round up

20
Q

What is the characteristic (of reticulated or stress PLTs) in citrated WB?

A

These are cylindrical and beaded

21
Q

What is the function (or characteristic when it comes to components) of reticulated or stress PLTs?

A

It carries free ribosomes and RER fragments

22
Q

What is the dye used for reticulated or stress PLTs?

A

Thiazole orange

Hematology 2 (Lecture) (11 decks)

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