Plastictity And Functional Recovery Flashcards
What is brain plasticity
Brains ability to change and adapt as a result of experience and new learning
Experience expectant plasticity
Changes in the brain only take place during infancy and childhood
Experience dependent plasticity
Brain continues to create new neural pathways and alter existing ones as a result of learning and life experiences
Synaptogenesis
New synapses are formed
Occur throughout life but during infancy there is an explosion of synaptic formation - exuberant synaptogenesis
Neurogenesis
New neurons are grown
In infancy - responsible for populating the growing brain with neurons
Also occurs in childhood
Synaptic pruning
Process of synapse elimination
Typically happens between early childhood and the onset of puberty
Can occur to a lesser extent in adulthood
Effects of infancy on brain plasticity
Brain experiences rapid growth in the number of synaptic connections
Peaks at approx 15,000 by the age of 2-3 years old
Twice as many as adult brain
As we age - rarely used connections are deleted and frequently used connections are strengthened
Kuhn et al - computer gaming
Illustrated potential benefits of playing supermario for 2 months - 30 mins a day
Significant increases in neural connections in hippocampus and prefrontal cortex
Responsible for key behaviours such as memory planning and motor performance
Supports synaptogenesis
Maguire et al - taxi driving
Studied brains of London taxi drivers
Used mri
Found more grey matter in prosterior hippocampus than in matched control group
This part of brain associated with development of spatial and navigational skills
Koppelmans et al - astronauts
Studied effect of no gravity in space and how this affects brain
27 astronauts brain scanned before a space mission then again upon return
Between 2 weeks - 6 months = cerebellum shrunk
Motor and somatosensory regions swollen
Neural regeneration
Aka axon sprouting
Occurs when new nerve endings grow and connect with undamaged areas
Compensate for damaged areas and enable recovery of previously lost functioning
Type of synaptogenesis
Neuronal unmasking
Occurs when dormant synapses in the brain are opened and become functional
Occur when surrounding brain area becomes damaged as the rate of input to these dormant synapses would increase opening connections to regions of the brain that are not normally activated allowing the gradual development of new structures
Type of synaptogenesis/neurogenesis
Neural reorganisation
When brain transfers functions from the damaged area to undamaged sections of brain
Eg brocas on left damaged - right takes over