Plasticity & Functional Recovery Of The Brain After Trauma Flashcards

1
Q

What is plasticity?

A

The brains tendency to change or adapt, functionally and physically because of new learning and experience - involving the growth of new connections

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2
Q

What are connections?

A

New experiences, means that the nerve pathways are used frequently, developing stronger connections

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3
Q

What is synaptic pruning?

A

Neurons that are rarely used or never used eventually die/get deleted

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4
Q

What are the supporting evidence studies for plasticity?

A

Boyke et al (2008) & Maguire et al (2000)

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5
Q

What did Boyke (2008) find?

A

He evidence of brain plasticity in 60 year olds that were taught a new skill - juggling. An increase of grey matter in the visual cortex, although when practiced stopped, these changes reversed

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6
Q

What did Maguire (2000) find?

A

16 male taxi drivers and 50 non taxi drivers were studied to check the volume of grey matter - they found that the taxi drivers posterior hippocampus was significantly larger compared to the non drivers (associated with spatial & navigation skills

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7
Q

What are the evaluation points for Maguire (2000)?

A

+ MRI scans - empirical
- Low population validity - 16 male taxi drivers
- Correlational - no cause or effect
+ Age and plasticity - Ladina Bezzola et al (2012)

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8
Q

What is functional recovery?

A

A form of plasticity following damage through trauma, the brain can redistribute or transfer functions usually performed by damaged areas to undamaged areas

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9
Q

What is the physical injury used to display functional recovery?

A

A stroke

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10
Q

What happens to the brain during recovery?

A

The brain can rewire and reorganise itself by forming new synaptic connections close to the area of the damage

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11
Q

What are the 3 structural changes in the brain that support this process?

A
  1. Axonal sprouting
  2. Denervation supersensitivity
  3. Recruitment of homologous areas on the opposite side of the brain
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12
Q

What is axonal sprouting?

A

The growth of new nerve endings which connect with other undamaged nerve cells to form new neuronal pathways

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13
Q

What is denervation supersensitivity?

A

Axons that do a similar job become aroused to a high er degree to compensate for lost ones - however this can cause over sensitivity to messages relating to pain

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14
Q

What is recruitment of homologous areas?

A

Recruitment of similar areas on the opposite side of the brain happens so that specific tasks can still be performed

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15
Q

What is the study for functional recovery?

A

Danelli et al (2013)

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16
Q

What did Danelli (2013) study?

A

Examined a patient called EB who had his left hemisphere removed due to a tumour, at the time his linguistic abilites disappeared. After long rehab, by 5 his language abilities improved and was tested again at 17, Danelli found that his RH compensated for the loss of the left hemisphere - there were some minor grammatical errors and lack of speed - but generally he was functioning well

17
Q

What are the evaluation points for Danelli (2013)?

A

+ Supporting evidence - EB
- Low population validity - 1 case study
- Case study - unrepresentative