plasticity + functional recovery of brain after trauma Flashcards

1
Q

plasticty

A

-shaped or molded easily
-in brain: its braisn ability to adapt as a rresult of experince or learning
-can adapt functionally or physically

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2
Q

infancy

A

-kids learn fast
-rapid growth in synaptic transmissions
-reach around 15,000 connectiosn between ages 2-3yrs nearly 2x as many as human brain
-we dont keep all connections

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3
Q

synaptic pronning

A

-as we age:
1) rarely used connections r deleted
2) frequently used ones are strengthened
-allows r brain to have life long plasticity, where new neural connections r formed in response to new demands on the brain

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4
Q

gray matter

A

-contains neuronal cell bodies
-found in outer cortex of brain

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5
Q

white matter

A

-primarily consists of myelinated axons
-found closer to the center of the brain

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6
Q

ao3

Draganski et al (2006)

A

-scanned the brains of medical students three months before and just after final exams
-Changes were found in the hippocampus and parietal cortex

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7
Q

ao3

Negative plasticity

A

The brain’s adaptation to prolonged drugs use leads to poorer cognitive functioning in later life (Medina et al, 2007)

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8
Q

ao3

Age and plasticity

A

-40 hours of golf training produced changes in neural representations of movement in participants aged 40-60

-The researchers used fMRI and observed increased motor cortex activity in the novice golfers compared to a control group

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9
Q

functional recovery

A

-example of plasticity
-brains ability to redistribute or transfers functions usually formed by a damage area to another undamaged area
-

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10
Q

spontaneous recovery

A

-FR can happen quickly after trauma
-this process can slow down after several weeks/months
-plasticty slows w age
- after this, redistribution therpay can be used to help indivual w/ their recovery (neurorehabilitation)

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11
Q

what happens during functional recovery?

A

-brain rewire+ reoraganise istelf by forming new synaptic connections close to area of damage
-neural pathways that arent normally used to carry out specific function will activate
-neural regnation + neural reorganisation can occur thru diff egs of structural change

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12
Q

ao3 support

schneider et al (2014)

A

-more time ppl w/traumatic brain injury had spent in education, greater chances of disaability free recovery
-40% those w/disability free recovery had 16yrs +education, 10% who had 12 yrs
-had to score 0 to be disability free
-collects quantitive data
-0 doesnt exclude possibility of subtle functional challenges
-retested after yr of injury

CP: FR should work for all this shows it doesnt. quantitive=not open pic

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13
Q

ao3 support

Baneriee et al (2014)

A

-Treated people with a total anterior circulation stroke (TACS)
- treated w stem cells (cells that can specialise into any cell) in a medical trial
-The recovery rate for this trial was 4% higher than the typical recovery rate
-Only 5 participants were used
-The treatment was intrusive (they had to put the stem cells into the participants)
-No control group was used

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14
Q

ao3 strength

neurohabilitation

A

-sucess of it=strength of fr
-the industry of axanol growth has been able to contribute to how well therapy works
-understanding of fr allows medical pros to know when to intervene

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15
Q

structural chnages fr

Axonal sprouting

A

The growth of new nerve endings which connect with other, undamaged nerve cells to form new neural pathways

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16
Q

structural changes fr

Denervation supersensitivity

A

Occurs when axons that do a similar job become aroused to a higher level to compensate for the ones that are lost

17
Q

structural changes fr

Recruitment of homologous areas

A

Areas on opposite sides are used so that specific tasks can still be performed