plasticity and functional recovery of the brain after trauma Flashcards

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1
Q

explain what brain plasticity is

A
  • the brain’s tendency to change and adapt as a result of experience and new learning
  • involves growth and new synaptic connections made. Peaking about 15,000 per neuron at 2-3 yrs old (Gopnik et al. 1999)
  • as we age, rarely used connections are deleted and frequently used connections are strengthened known as synaptic pruning.
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2
Q

who researched brain plasticity

A

Maguire et al. (2000)

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3
Q

explain the research into brain plasticity

A
  • Maguire studied the brains of London taxi drivers and found they had significantly more volume of grey matter in the posterior hippocampus than in a matched control group. This part of the brain is associated with the development of spatial and navigational skills.
  • this makes sense considering that to become a taxi driver you have to take a knowledge test which assesses their recall of the city streets and possible routes
  • also found that the longer they had been taxi drivers the more pronounced was the structural difference (positive correlation)
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4
Q

who else conducted research into brain plasticity?

what did they find?

A
  • Graganski et al (2006)
  • studied brains of medical students three months before and after taking their final exams.
  • learning induced changes were seen to have occurred in the posterior hippocampus in the parietal cortex presumably as a result of learning.
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5
Q

explain functional recovery after brain trauma

A
  • unaffected areas of the brain are often able to adapt and compensate for those areas that are damaged.
  • the functional recovery that may occur is an example of brain plasticity.
  • scientists suggest that this may occur very quickly after trauma and then slow down after several weeks or months
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6
Q

what happens in the brain during recovery

A
  • brain is able to re-wire and reorganise itself by forming new synaptic connections close to the area damaged
  • secondary neural pathways that would not be typically used to carry out certain functions are activated to enable functioning to continue (Doidge 2007)
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7
Q

what structural changes happen in the brain during recovery? (3)

A
  • Axonal sprouting= growth of new nerve endings which connect with other undamaged nerve cells to form new neuronal pathways
  • denervation super sensitivity= axons that do a similar job become aroused to a higher level to compensate for the ones lost. However it can have negative consequences of oversensitivity to messages such as pain.
  • recruitment of homologous areas on opposite sides of the brain = means that specific tasks can still be performed. E.G. if Broca’s area on the right was damaged, the left side would be able to take over.
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