Plasmodium, Babesia, Leishmania, Trypanosomes Flashcards
Plasmodium falciprum schizont
Plasmodium falciprum early troph
Plasmodium vivax early trophozoite
Plasmodium malariae early troph
Leishmania tropica
infection route: phlebotomus (sand fly), multiplies in human macrophages
geography: urbal middle east
Lab test: skin scrapings, H+E stain, find amastigotes
pathology: Oriental sore, tropical sore, or Old World Cutaneous Leishmaniasis
skin ulcerations - self healing
Leishmania braziliensis
Life cycle: same as L. mexicana (Lytzomyia mosquito)
Geography: South america
Lab Diagnosis: nose cartilage biopsy
Pathology: Espundia (mucocutaneous nose disfiguration)
Plasmodium vivax developing troph
Leishmania major
vector - Phlebotomus sand fly
human host - multiplication in macrophages
geography: rural middle east, afghanistan, africa
Lab test: skin scrapings, H+E stains, find amastigotes
pathology: self healing sore
Trypanosoma brucei
Life cycle: vector teste fly, trypomastigotes in blood, lymph, CSF
Geography: West Africa (chronic) , East Africa (actue)
Lab Diagnosis: thick/thin smears, w/ tryapnosomes
Pathology: African Sleeping Sickness. Winterbottoms sign, fever, headache, coma
Plasmodium vivax
Life cycle: anopheles, blood transfusion, congenital geography: tropics, subtropics, temperate climates Lab tests: thick/thin blood smears, molecular method, serology Pathology: Benign tertian ( 48 hr), quartan ( 72 hr), benign tertian, 24 hr May present first with headache, photophobia, muscle aches, anorexia, nausea, sometimes vomiting Paroxysms - chills, shivering - fever, sweats merozoites released and produce the fever
Plasmodium falciprum troph
Plasmodium ovale gametocyte
Plasmodium ovale
life cycle: anopheles, blood transfusion, congenital geography: west africa, south pacific lab tests: thick/thin blood smear, molecular, serology Pathology: same as P malariae, and P vivax
Plasmodium ovale troph
Plasmodium malariae troph