Plasma Proteins Flashcards

1
Q

Protein comes from the Greek word

A

proteios, meaning “first ranked of importance”.

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2
Q

Proteins are synthesized in the liver and secreted by the hepatocytes into the circulation, except

A

immunoglobulins

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3
Q

immunoglobulins are from what type of cells

A

plasma cells

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4
Q

amino acids are linked to another via a

A

peptide bond

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5
Q

is formed when the carboxyl (-COOH) group of one amino acid links to the amino
(NH2) group of another amino acid with the loss of a water molecule.

A

Peptide bond

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6
Q

End of protein structure with a free amino group.

A

N-terminal

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7
Q

End of protein structure with a free carboxyl group.

A

C-terminal

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8
Q

Proteins consists of –% nitrogen, which differentiates proteins from
carbohydrates and lipids

A

16%

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9
Q

It is the linear sequence of the amino acids

A

primary structure

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10
Q

It involves the winding of the polypeptide chain.

A

secondary structure

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11
Q

It is the actual three-dimensional configuration; the
folding pattern of proteins.

A

tertiary structure

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12
Q

It is the actual three-dimensional configuration; the
folding pattern of proteins.

A

Quaternary Structure

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13
Q

protein that has no quarternary structure

A

albumin, it is a single polypeptide chain

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14
Q

They contain peptide chains which on hydrolysis yield only amino acids

A

Simple Proteins

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15
Q

Composed of protein (apoprotein) and nonprotein (prosthetic group) components

A

Conjugated Proteins

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16
Q

Protein with 10 – 40% carbohydrates attached (e.g., haptoglobin)

A

Glycoproteins

17
Q

Protein with >40% carbohydrates attached

A

Mucoproteins

18
Q

It is a balance between anabolism (synthesis) and catabolism (breakdown)

A

NITROGEN BALANCE

19
Q

It is when a protein catabolism exceeds anabolism

A

Negative Nitrogen Balance

20
Q

It is when anabolism is greater than catabolism.

A

Positive Nitrogen Balance

21
Q

It is characterized by excessive tissue destruction seen in burns, wasting
disease, high fever, and starvation

A

Negative Nitrogen Balance

22
Q

Indicator of malnutrition

A

prealbumin/transthyretin

23
Q

prealbumin/transthyretin in poor nutrition

A

decreased

24
Q

major contributor to oncotic pressure

A

albumin

25
Q

albumin level in dehydration

A

increased

26
Q

albumin is a sensitive and highly prognostic marker in cases of..

A

cystic fibrosis

27
Q

major immunoglobulin in serum

A

IgG

28
Q

first immunoglobulin made by fetus

A

IgM

29
Q

only immunoglobulin that crosses the placenta

A

IgG

30
Q

major immunoglobulin found in secretions

A

IgA

31
Q

found in B cell surface and serves as receptor for antigen

A

IgD

32
Q

least common serum immunoglobulin

A

IgE

33
Q

involves in allergic reactions cause it binds to basophils and mast cells

A

IgE

34
Q

3rd most abundant immunoglobulin

A

IgM

35
Q

burnt sugar odor to urine, breath, skin

A

maple syrup urine disease

36
Q

sweaty feet odor of urine and skin

A

isovaleric

37
Q

urine has cabbage odor

A

tyrosemia