Plasma Protein Flashcards
Highest protein concentration
Albumin
Causes of hypoproteinemia
Dehydration
Multiple myeloma
Autoimmune disease
Neoplasia
How do you calculate for globulin
Total protein - Albumin
Normal AG ratio
0.8-2.0
Decreased AG ratio
Multiple myeloma
Autoimmune disease
Chronic inflammation
Increased albumin
Dehydration
Decreases globulin
Immunodeficiency
Marker of nutritional status
Severity of illness
Prealbumin
Transthyretin
Produced by the lungs and liver
Acute phase reactant
Neutralizes enzymes
AAT
Binds to hemoglobin and prevent excretion by the kidneys
Seen in intravascular hemolysis
Haptoglobin
Decreased ceruloplasmin
Wilson’s disease
Malnutrition
Liver disease
Evidence of multiple myeloma
Hypercalcemia
Renal insufficiency
Anemia
Bone lesion