Hemoglobinopathies And Polycythemia Flashcards
1
Q
Alpha like globin
A
Chromosome 16
2
Q
B like globin
A
Chromosome 11
3
Q
Predominant hemoglobin in adults
A
Hgb A
4
Q
Causes by impaired production of polypeptide chains
A
Thalassemia
5
Q
Severe hypochromic, microcytic anemia, hepatomegaly
A
Major beta thalassemia
6
Q
Probably the most common single gene disorder in humans
A
Alpha thalassemia
7
Q
Complete absence of alpha chains
A
Barts hydrops fetalis
8
Q
3 out of 4 alpha is missing
A
Hgb H
9
Q
Most common hemoglobinopathy
A
Sickle cell trait AS
10
Q
Found mostly among blacks
A
HbSS
Sickle cell disease
11
Q
Positive for sickling test
A
Sickling disorder
12
Q
Reduced plasma volume
A
Relative PV
13
Q
An increase in HCT and RBC
Not total red cell mass
A
Relative PV
14
Q
BM is erythroid hyperplasia
A
Absolute PV
15
Q
Commonly used tracer for erythrocyte volume
A
51Cr
