Plasma Cell Dyscrasias Flashcards
1
Q
Diagnosis of multiple myeloma
A
- serum and urine protein electrophoresis-M protein spike, monoclonal
- measurement of serum quantitative immunoglobulins with immunofixation
- 24 hr urine protein electrophoresis with immunofixation
- radio graphic bone survey
- bone marrow biopsy: bone marrow clonal plasma cells or plasmacytoma
- end organ damage
2
Q
Treatment of multiple myeloma
A
-stem cell transplant for
3
Q
Multiple myeloma features
A
- anemia with rouleaux formation
- kidney disease
- hypercalcemia
- vertebral compression fractures, osteoporosis, osteopenia, lytic bone lesions
- hyper viscosity syndrome,
