Plasma cell Flashcards
1
Q
What organelles create the appearance of the off-center nucleus and abundant cytoplasm in a plasma cell?
A
The rough endoplasmic reticulum and Golgi apparatus are plentiful
- Remember:*
- The plasma cell is a protein (antibody) factory!*
2
Q
How are plasma cells formed?
A
When B cells encounter a recognized antigen, they differentiate into plasma cells (which have antigenic memory)
3
Q
You note that a patient’s bone marrow shows a monoclonal proliferation of plasma cells; what is the diagnosis?
A
Multiple myeloma
4
Q
Description of chromatin distribution
A
Clock-face
5
Q
Where are plasma cells found?
A
Found in bone marrow and normally do not circulate in peripheral blood
