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Blood Bank 2: Summer 2024 > Plasma > Flashcards

Plasma Flashcards

1
Q

How to administer plasma

A

Thaw first
Must predict when pt may need plasma since thawing takes time

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2
Q

Why administer plasma?

A

Patient may be missing coagulation factors, so plasma transfusion replenishes those coag factors

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3
Q

How many bags to pool cryoprecipitate in?

A

5 bags

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4
Q

Cryoprecipitate used for

A

Fibrinogen replacement

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5
Q

FFP vs FP24

A
  • FFP: fresh frozen plasma frozen within 8 hrs
  • FP24: frozen plasma frozen within 24 hrs and has less coag factor than FFP
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6
Q

When to use FFP

A

Treat coag factor deficiency bc has all coag factors

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7
Q

When to use FP24

A
  • Transfusions
  • Increase blood volume, pt has most or all coag factors
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8
Q

When to use liquid plasma (was never frozen)

A

Trauma situations

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9
Q

Liquid plasma expiration date

A

5 days after whole blood, so real number ~26 days

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10
Q

T/F
Liquid plasma is good to give to a patient with coag factor deficiency bc it contains most/all coag factors

A

False
Coag factors greatly diminished

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11
Q

Frozen plasma storage

A

< -18°C for up to 1 yr

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12
Q

How to prep cryoprecipitate

A

Slowly thaw FFP at 1-6°C, remove liquid, then resuspend solid components in 15ml leftover plasma

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13
Q

Cryoprecipitate storage

A

<-18°C up to 1 yr
Thaw at 37C and store at RT until expiration

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14
Q

Cryoprecipitate expiration after 37°C thaw

A
  • 4 hr for pools
  • 6 hr for singles
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15
Q

What is cryo-reduced plasma?

A

Leftover plasma from making cryoprecipitate

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16
Q

What does cryo-reduced plasma contain?

A

Plasma proteins and ADAMTS13

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17
Q

Cryo-reduced plasma storage

A

< -18°C up to 1 yr

18
Q

Cryo-reduced plasma uses

A

Best for TTP patients because ADAMTS13 helps replenish platelets

19
Q

List plasma fractions

A
  1. Activated Factor VII
  2. Factor VIII
  3. Prothrombin complex with vit K-dependent factors (II, VII, IX, X)
  4. FIX
  5. Antithrombin III

Factors 7, 8, and 9

20
Q

When to use activated FVII and con of using it

A
  • Massive bleeding
  • Con: spontaneous thromboli
21
Q

When to use FVIII and pro

A
  • Hemophilia A treatment, replacing cryoprecipitate treatment
  • Pro: safe from HIV now
22
Q

When to use prothrombin complex and con

A
  • Massive bleeding
  • Con: DIC or thrombosis possible
23
Q

When to use FIX

A

Hemophilia B

24
Q

When to use antithrombin III

A

Prevent thromboembolism in surgical cases

25
Q

When to give vit K

A

Pts missing coag factors or surgery

26
Q

List more uses for plasma fractions

A
  • IVIG or IMIG for immunocompromised pts
  • Rhogam
  • Normal serum albumin for shock/burn pt
  • Lactated ringers
  • Dextran
  • HES
27
Q

Does convalescent plasma have to be ABO compatible?

A

Yes

28
Q

Convalescent plasma uses

A
  • Passive immunity
  • Stop-gap treatment when no known treatment exists
  • Good for immunocompromised
29
Q

You see pinkish plasma during visual inspection. What happened?

A

Hemolysis

30
Q

You see lots of bubbles, clots, and fibrin strands in plasma upon visual inspection. What happened?

A

Bacterial contamination

31
Q

You see particulate matter that does not dissipate upon shaking. What happened?

A

Coag cascade activated

32
Q

You see green plasma and it is normal. Why is it normal?

A

Woman on birth control

33
Q

Plasma pre-transfusion testing

A

Just do ABO fwd and rvs type and rely on labels (no Ab screen)

34
Q

Does Rh matter for plasma matching?

A

No

35
Q

T/F
Must do crossmatch for plasma transfusion

A

No

36
Q

85% of people okay with what type of plasma if AB not available?

A

Type A

37
Q

What must be confirmed on blood product?

A
  • Pt ID
  • Unit ID
  • Blood types
  • Visual inspection
38
Q

T/F
Plasma cannot be issued same time as another blood product

A

False
It can be infused at the same time as another blood product

39
Q

List coag tests to monitor transfusion

A
  • PT/INR
  • PTT
  • Fibrinogen
  • Bleeding time
  • DDimer
40
Q

List hematology tests to monitor transfusion

A
  • Hct
  • Plt count
41
Q

Which product is stored incorrectly?
A. Thawed FFP in 2-6°C fridge
B. Platelets on ice
C. Cryoprecipitate at RT
D. FP24 in < -18°C freezer

A

B. Platelets on ice
Platelets must be stored at room temp (20-24°C

Blood Bank 2: Summer 2024 (8 decks)

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