Donor selection Flashcards
Blood inventory management
Volunteer donors (40% US population eligible, but <10% actually donate)
List process of donating blood
- Donor selection: registration, ID donor, donor education
- Eligibility: questionnaire, mini-health physical
- Collection: phlebotomy and post-donation care
Acceptable types of ID
- donor card
- driver’s license
- passport
- school ID (must be age > 16)
How long do you have to wait to donate if you donated whole blood?
56 days
How long do you have to wait to donate if you donated double RBCs?
112 days
up to 3x a year
How long do you have to wait to donate if you donated platelets?
7 days according to Red Cross
2 days according to FDA
up to 24x a year
How long do you have to wait to donate if you donated plasma?
28 days
up to 13x a year
Steps of donor ID
- Photo ID
- Check date of last donation
- Deferral status checked
- Consent to donate - signed form
Donor education
- the donation process
- infectious disease transmission via transfusion
- circumstances when testing isn’t done
Why may infectious disease testing not be done?
- tests available but may not detect early-stage or window-period infection
- tests available but not universally used by donor centers
- no licensed tests available for donor screening
No licensed tests available for donor screening for which diseases?
- babesiosis
- CJD
- malaria
Mini-physical: general appearance
- Skin free of scars and needle marks
- Eyes clear, no pupil dilation, no yellow sclera
Mini-physical: H/H
- Female Hgb > 12.5 g/dl for females
- Male Hgb > 13.0 g/dl
Mini-physical temp
No greater than 37.5 C or 99.5 F
BP and pulse criteria
- BP<180/100
- pulse 50-100 bpm
Weight
Weight > 110 pounds
Which infectious agents are ruled out by questioning only?
- malaria
- prions
- Ebola
Which infectious agents are ruled out by donor testing only?
- WNV
- Chagas
Which infectious agents are ruled out by both questioning and testing?
- HIV
- HBV
- HCV
- Zika
- Babesia
- Syphilis
Which infectious agent must test negative for specific recipients?
CMV
Blood collection must not exceed ____, otherwise
- 15 min
- throw away bag if exceed 15 min
List donor possible adverse reactions
- Vasovagal reaction (fainting)
- Hyperventilation
- Hypotensive shock
- Hematoma
- Twitching/muscle spasms
- Cardiac difficulties
How to treat vasophagal reaction?
- Stop phlebotomy
- Elevate legs above head
- Cold compress forehead and neck
- Aromatic spirits
For donation from relative
Lower risk of:
Higher risk of:
- Lower risk of alloimmunization
- Higher risk of disease transmission, graft vs host disease
Autologous donation associated with higher risk of ___
Transfusion associated circulatory overload (given more blood than needed) (TACO)
How to handle accepted donor who weighs < 110 lbs
Calculate anticoag amount for low volume
Deferral time for potential bacterial contamination or donor health
Today
Deferral time for aspirin for platelets
48 hrs
Deferral time for vaccines (LAV) or antibiotics
2 wks
Deferral time for pregnancy
6 wk
Deferral time for past donation
8 wks*
depends on type of donation
Deferral time for risky behavior, treated STD, transfusion
3 months
Deferral time for incarceration
12 mth
Deferral time for positive Babesia NAT test
2 yr
Deferral time for malaria infection or living in malaria-endemic location
3 yr
Deferral time for:
- positive Hep or HIV test
- CJD risk
- bleeding condition
- heart or lung condition
permanent/indefinite
Why test for ABO and Rh in donor testing?
Detect weak subgroups and weak D
List required infectious disease testing and deferral categories
- permanent: HBV/HCV, HIV
- temporary: WNV, syphilis, Babesia
- indefinite: T.cruzi Ab
Syphilis testing
- Screen w RPR and hemagglutination
- Confirm with FTA-ABS or other FDA-approved EIA test
How to decrease treponemal risk of transmission?
Cold storage bc treponemes are fragile and sensitive to cold
Syphilis deferral time
12 mth post-treatment
HCV deferral
permanent
HTLV deferral
permanent/indefinite
WNV deferral
120 days
Zika deferral
4 wks
COVID-19 deferral
14 days for symptoms or pos antigen test
blood donations not tested for COVID-19
no deferral for vaccine or pos antibody test
LAV deferral
2-4 wk
Synthetic vaccine deferral
none
List medications that get you deferred
- Abx
- GH
- HepBIG
- Plavix
- Accutane
- Tegison
- Aspirin
Which virus is not detected through NAT?
HCV
HBV
HTLV
WNV
HTLV bc no risk