Plasma Flashcards
What is plasma
Liquid component of blood (around 55% of volume)
What is buffy coat
Leukocyetes and platelets (around 1% of blood)
Serum vs plasma
Serum has no clotting factors
Serum separator tubes (SST) contain
A silica coating which induces clotting
A layer of gel forming a physical barrier between cells and serum
4 main fluid compartments
Intracellular
Extracellular;
Interstitial fluid i.e. fluid between cells
Transcellular fluid e.g. cerebrospinal fluid (CSF), ocular fluids
Plasma
Functions of plasma
Clotting
Immune defence (antibodies & complement proteins)
Osmotic pressure maintenance
Metabolism (nutrients)
Endocrine (many hormones)
Excretion
What are the 2 major types of plasma protein
Serum albumin
Globulins
Serum albumin is produced by
The liver
Serum albumin key function
Transport (lipids, hormones,ions)
Osmotic pressure maintenance
A1AT ***
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