Placenta Flashcards

1
Q

What is the connecting stalk made of?

A

Extraembryonic mesoderm

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2
Q

What happens to cytotrophoblast cells when they migrate into the syncitotrophoblast?

A

Fuse and lose their membranes

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3
Q

Why does the chorionic sac dissapear?

A

Amniotic sac enlarges

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4
Q

What is the chorion made of?

A

Trophoblast

(Somatic) extraembryonic mesoderm

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5
Q

Why do decidual cells stain pale?

A

High glycogen and lipid

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6
Q

What is placenta accreta?

A

Chorionic villi attach to myometrium

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7
Q

What is the decidua?

A

The functional latter of the endometrium that separates form the remainder of the uterus after parturition.

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8
Q

What happens for the placental barrier to thin over pregnancy?

A

Cytotrophoblast regresses
Syncitiotrophoblast thins
Margination of capillaries

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9
Q

Where does choriocarcinoma typically spread early?

A

Lungs

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10
Q

What is the role of hPL?

A

Increase glucose availability to the foetus

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11
Q

What Ig is passed across the placenta and by what process?

A

IgG

RME

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12
Q

Teratogen exposure during what period gives low risk of structural defects?

A

After embryonic period expect the CNS>

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13
Q

What should symphysis fundal height be at 20 weeks?

36 weeks?

12 weeks?

37-40 weeks?

Post-partum

A

Umbilicus

Xiphersternum

Pubis synthesis

Regression of fundal height

Back at umbilicus

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14
Q

When should the first US scan be between ideally?

A

11w-13w6days

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15
Q

What does nuchal translucency test for?

A

Detect cardiovascular developmental issues

Downs
Di George
Body-stalk abnormalities

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16
Q

When is the second scan usually?

What is measured?

A

20 weeks

Confirmation of viability
Feral head
Biparietal diameter
Femur length

17
Q

What is biparietal diameter used in combination in combination with other measures to do?

A

Date pregnancy in T2 and T3

18
Q

What is average birth weight?

What weight is macrosomia classed as?

A

3.5kg

Above 4.5kg

19
Q

Give some issues with growth restriction.

A
Low birth weight
Hypoxia 
Hypoglycaemia 
Meconium aspiration 
Trouble maintaining body temperature 
Abnormal high RBC count
20
Q

What 2 things occur during the terminal sac stage (week 26)?

A

Terminal sacs begin to bud from the resp bronchioles

Difefrentiation of TI and TII pneumocytes

21
Q

What is normal foetal heartrate?

A

120-160bpm

22
Q

What are some complications of oligohydramnios?

A

Cord compression
MSK (facial distortion, club foot)
Pulmonary hypoplasia
Intrauterine growth restriction

23
Q

What are some complications of polyhydraminos?

A

Faetal malposition
Umbilical cord prolapse
Abruption placentae
Preterm contractios and labour

24
Q

When does the baby start to move?

When does the quickening occur?

A

17th week