Placenta Flashcards

1
Q

When can sperm move through the cervix

A

When oestrogen levels are high just before ovulation

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2
Q

What activates meiosis 2

A

Sperm entry and Ca2+ spikes

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3
Q

What are the two differentiatied cell populations in the early embryo

A

Inner cells mass and trophectoderm

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4
Q

What is nidation

A

When the embryo implants int he decidua

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5
Q

What stage are the uterine glands torturus

A

Secretory/ early luteal

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6
Q

What is basal vacolutaion

A

When the stromal cells have vesicles in them of glandular secretions occurs in pre secretory phase

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7
Q

When does the villous period of the placenta begin

A

12 days post conception (3-4 weeks)

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8
Q

Once villous stage is reached what is occuring

A

Trophectoderm form cytotrophoblast which extends into intervillous spaces (ex lacunae) surrounded by syncytiotrophoblast. Primary villi formation

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9
Q

When do secondary villi form

A

When extraembryonic mesenchyme begins to infiltrate the primary villous

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10
Q

When do primary villi form

A

18-20 days post conception when fetal capillaries form in secondary villi

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11
Q

Describe the two forms of villi

A

Floating- mostly these are for transfer. Anchoring villi (cytotrophoblasts break through syncitiotrophoblast and invade amternal tissue.

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12
Q

What form the definitive placenta

A

Chorion frondosum

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13
Q

What forms chorinic membrane

A

Chorion levae

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14
Q

Incidence of pre-eclampsia

A

3-8%

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15
Q

What is the increased risk for mother if PE before 34 weeks

A

CVD

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16
Q

What does the polar trophectoderm go on to form

A

Primitive syncitium

17
Q

What are the gaps formed by the invasion of the primitive syncitium called

A

Lacunea

18
Q

What are the extension of primitive syncitium called

A

Trabeculae

19
Q

When the embryo has implanted what does the primitive syncitium become

A

trophoblast

20
Q

What is a clinical miscarriage

A

Once FHR heard (5-6/40)

21
Q

What cells invade the maternal spiral arteries

A

Extravillous cytotrophoblasts

22
Q

What causes inadequate placentation

A

Inadequate invasion of the spiral arteries

23
Q

When do trophoblast plugs occur until

A

12/40