Placenta Flashcards
1
Q
How does the morphology change grossly?
A
Over entire chorionic surface, then regresses to discoid form.
2
Q
Outline unplugging.
A
At beginning plugged by trophoblasts.
Loss of smooth muscle and elastic tissues from arterial wall as far as inner 1/3 of myometrium
Mediated by invading trophoblasts.
3
Q
How are fatty acids transported?
A
Preferential for long chain PUFAs.
Passive or carrier
Bind intravenous at FABP
Basal membrane FA transporters - CDc36
Fetal circulation bound to alpha fetal protein.
Re-esterified in liver.
4
Q
What are the four mechanisms for excretion of various milk products?
A
Exocytotic
Milk fat
Transporters
Vesicular transcytosis - immunoglobulins
Paracellular - leukocytes
5
Q
What does suckling stimulate?
A
VIP release
Inhibition of dopamine.
