Pituitary dwarfism Flashcards

1
Q

Incidence

A
  • Clinical signs
  • Affects German shepherds more
  • Simple autosomal recessive
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2
Q

embryological origin

A
  • constriction of growth of Rathke’s pouch
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3
Q

Growth features

A
  • Diminishes a few weeks after birth
  • Growth plates open or closed
  • Activity level normal
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4
Q

lab characteristics of pituitary dwarfism

A
  • Low values
    • Basal GH
    • GH post clonidine
    • IGF-1
    • Basal T4
  • normal values
    • T4 post TSH
    • Basal cortisol
    • Cortisol post ACTH (don’t have to worry about Addison’s)
  • inc insulin sensitivity
  • dec gonadotropin
  • dec prolactin
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5
Q

Treatment dwarfism

A
  • Drugs can be dangerous
  • don’t have to treat
  • GH is expensive
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