Pituitary dwarfism Flashcards
1
Q
Incidence
A
- Clinical signs
- Affects German shepherds more
- Simple autosomal recessive
2
Q
embryological origin
A
- constriction of growth of Rathke’s pouch
3
Q
Growth features
A
- Diminishes a few weeks after birth
- Growth plates open or closed
- Activity level normal
4
Q
lab characteristics of pituitary dwarfism
A
- Low values
- Basal GH
- GH post clonidine
- IGF-1
- Basal T4
- normal values
- T4 post TSH
- Basal cortisol
- Cortisol post ACTH (don’t have to worry about Addison’s)
- inc insulin sensitivity
- dec gonadotropin
- dec prolactin
5
Q
Treatment dwarfism
A
- Drugs can be dangerous
- don’t have to treat
- GH is expensive