Pituitary disorders Flashcards
What is the posterior pituitary formed from?
Brain tissue
What is the function of LH?
Causes ovulation and secretion of sex hormones
What is the function of FSH?
Sperm and egg development
What is the function of GH?
Skeletal growth, metabolism, muscle strength, bone density and cardial function
Stress causes the release of which hormone?
ACTH or adrenocorticotrophic hormone
In men, what are the functions of FSH and LH?
FSH drives sperm production whilst LH drives testosterone production
Somatostatin ….. the release of GH from the anterior pituitary gland.
Inhibits
In a primary hyperthyroidism, there will be high T4 and … TSH
LOW
In a secondary hyperthyroidism, there will be …. T4 and high TSH
High T4
What controls prolactin?
Dopamine
Diabetes inspidus is an … deficiency or resistance.
ADH
What are symptoms of diabetes inspidus?
Polydipsia, polyuria, high serum osmolality and low urine osmolality.
What are the features of hypopituitarism?
Poor growth in children, loss of body hair, lethargic and pallor
What is a prolactinoma?
A prolactin-secreting pituitary tumour
An ACTH secreting tumour will lead to ….. disease
Cushing’s
What are the symptoms of Cushing’s disease?
Rounded and plethoric face, central obesity with striae, easy bruising, proximal myopathy, hypertension and diabetes.
Which hormones should be tested with a basal pituitary test?
Those that are at relatively constant levels throughout the day
In a hormone deficiency dynamic test, would you stimulate or suppress the gland?
Stimulate the gland
An insulin tolerance test would be used to test if there is a growth hormone deficiency. Why?
The low glucose levels would reduce somatostatin release so we can see if GH is responding and if there is a correct reserve.
What is the anterior pituitary formed from?
Primitive gut tissue
