pineal gland Flashcards

1
Q

what is the pineal gland?

A

Pineal gland (or pineal body) is a pea-sized structure located in the centre of the brain

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2
Q

what does the pineal gland do?

A

secretes hormone melatonin

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3
Q

what is melatonin?

A

‘the hormone of darkness’

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4
Q

what causes the secretion of melatonin?

A

Eyes cue the pineal gland to secrete melatonin in response to darkness

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5
Q

what is the route of the neural pathway that leads to the secretion of melatonin?

A

The neural pathway responsible for secretion of melatonin passes through suprachiasmatic nucleus and via spinal chord and sympathetic neurons to the pineal gland.

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6
Q

what are the possible effects of melatonin (6)?

A
  • Help keep body’s circadian rhythms in synchrony with light/dark cycle induces natural sleep
  • Protects against damaging effects of free radicals
  • Slows ageing process
  • Enhances immunity
  • Melatonin may control sexual activity.
  • In some animals it control the seasonal fertility.
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7
Q

true or false - melatonin is classed as a drug?

A

false - Melatonin is not considered a drug in USA and is available from health food stores

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8
Q

what is melatonin used to treat?

A

In UK melatonin is prescription only medicine (POM) and has been licensed for the short-term treatment of primary insomnia characterised by poor quality of sleep in patients who are aged 55 or over

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9
Q

what is melatonin used to treat in children?

A

used in children with sleep disorders related to Attention Deficit Hyperactivity Disorder, autism, other developmental disabilities or visual impairment.

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10
Q

what are the 3 melatonin receptors?

A

MT1
MT2
MT3

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