phytochemicals Flashcards
Phytochemical
Sometimes referred to as phytonutrients.
any chemical or nutrient derived from a plant source.
In common usage have more limited definition. Usually refer to compounds found in plants not required for normal functioning of the body but which have a beneficial effect on health or an active role in the amelioration of disease.
Carotenoids
Functional components
Source
Potential benefits
Alpha-carotene Beta-carotene, Lutein
Carrots, Fruits, Vegetables
Neutralize free radicals, which may cause damage to cells
Dietary Fibre
what 3 fibres
Insoluble fibre, beta-glucan, soluble fibre
insoluble fibre
Beta-Glucan
soluble fibre
INsoluble fibre:What bran: Reduce risk of breast or colon cancer
Beta-glucan: Oats, barley, psyllium:
Reduce risk of cardiovascular disease.
Soluble fibre: psyllium: Protect against heart disease and some cancers; lower LDL and total cholesterol
Fatty Acids
2
Long chain omega -3 Fatty Acids-DHA/EPA
and
CLAs
Long chain omega -3 Fatty Acids-DHA/EPA
Conjugated Linoleic Acid (CLA)
Salmon and other fish oils: Reduce risk of cardiovascular disease. Improve mental, visual functions.
Cheese, meat products: Improve body composition. Decrease risk of certain cancers
Anthocyanidins
Fruits
Neutralize free radicals; reduce risk of cancer
Lignans
Flax, rye, vegetables
Prevention of cancer, renal failure
Tannins (proanthocyanidins)
Cranberries, cranberry products, cocoa, chocolate
Improve urinary tract health. Reduce risk of cardiovascular disease
Plant Sterols
Stanol ester
Corn, soy, wheat, wood oils
Lower blood cholesterol levels by inhibiting cholesterol absorption
Prebiotics/Probiotics
Jerusalem Fructo-oligosaccharides (FOS):
artichokes, shallots, onion powder
Improve quality of intestinal microflora; gastrointestinal health
Lactobacillus
Yogurt, Other dairy
Soy Phytoestrogens
Isoflavones: Daidzein Genistein
Soybeans and soy-based foods
Menopause symptoms, such as hot flashes Protect against heart disease and some cancers; lower LDL and total cholesterol
Antioxidant
Protect cells against oxidative damage and reduce the risk of developing certain types of cancer. Phytochemicals with antioxidant activity: allyl sulfides (onions, leeks, garlic), carotenoids (fruits, carrots), flavonoids (fruits, vegetables), polyphenols (tea, grapes).
Hormonal action
Isoflavones, found in soy, imitate human estrogens and help to reduce menopausal symptoms and osteoporosis
Stimulation of enzymes
Indoles, found in cabbages, stimulate enzymes that make estrogen less effective and could reduce the risk for breast cancer. Isothiocyanates, also from cabbages, stimulate expression of antioxidant enzymes. Other phytochemicals, which interfere with enzymes, are protease inhibitors (soy and beans), and terpenes (citrus fruits and cherries).
Interference with DNA replication
Saponins found in beans interfere with the replication of cell DNA, thereby preventing the multiplication of cancer cells. Capsaicin, found in hot peppers, protects DNA from carcinogens.
Anti-bacterial effect
- The phytochemical allicin from garlic has anti- bacterial properties.
Polyphenols
a compound containing more than one phenolic hydroxyl group.
Flavonoids – eg. flavonols, catechins, anthocyanins
Phenolic acids – caffeic acid, gallic acid
Isoflavones – genestein, diadzein
Lignans – eg. from flaxseed
Others – resveratrol, sesaminol, curcumin, capsaicin, ellagic acid, tannins, humulon, hydroxytyrosol
Organosulfur compounds
Diallyl sulfides
Dithiolthiones
Glucosinolates/isothiocyanates
Terpenoids
Monoterpenes – limonene, carvone
Triterpenes – limonin, nomilin
Saponins - ginsenosides
Ginkgolides
phytochemicals Differ from traditional nutrients in that
not necessary for normal metabolism and absence doesn’t result in a deficiency disease – at least not on the timescale normally attributed to such phenomena.
phtochemical effects on the body
Have many effects in the body. For example, they may promote the function of the immune system, act directly against bacteria or viruses, reduce inflammation, or be associated with the treatment and/or prevention of cancer, cardiovascular disease or any other malady affecting the health or well-being of an individual
Phenolics
hydroxyl group bonded directly to an aromatic hydrocarbon group
Anthocyanidins Catechins Flavonones Flavones Lignans Tannins (proanthocyanidins)
Catechins
Tea
Flavonones
vs. flavones
Citrus
fruit/vegetable