Physiology: Special Circulation Flashcards
What is the coronary circulation?
Coronary blood flow
- increases during heavy exercise
- 95% of coronary venous blood returns to coronary sinus, rest drains through the anterior coronary and thebesian veins
Coronary circulation is the shortest in the human body.
Where do the thesbian veins drain?
Left ventricle - slight deoxygenation of arterial blood
What are the special tasks of the coronary circulation?
Maintain high basal supply of oxygen
Increase the oxygen delivery in proportion to demand (e.g. in proportion to cardiac work)
What are the special features of cardiac muscle?
Size of muscle fibre diameter is small
Increased number of capillaries
What does a high density of capillaries allow?
Big surface area for oxygen transfer
Short diffusion distance into cardiomyocyte
What is important to note about the oxygen extraction?
Despite the high flow of blood, the myocardium has to extract 65%-75% if the oxygen to meet its demand.