Physiology of the Female Pelvis Flashcards
oral contraceptives
- inhibits ovulation and changes endo lining and cervical mucus
- contain estrogen and progesterone
- ovulatory phase should not occur
- nondominant follicles may be present
- endo appears as a thin echogenic line
luteinizing hormone
- essential in both males and females for reproduction
- secreted by the anterior pituitary gland
- increasing estrogen levels stimulate LH production
- increase triggers ovulation and initiates the conversion of the residual follicle into a corpus luteum. corpus luteum produces progesterone to prepare the endo for possible implantation
- LH surge typically lasts only 48 hours
LH releasing factor
becomes active after puberty
produced by the hypothalamus
released into the bloodstream, reaching the anterior pituitary gland
luteinizing hormone
hormone that stimulates ovulation
FSH releasing factor
- becomes active before puberty
- produced by the hypothalamus
- released into the bloodstream, reaching the anterior pituitary gland
- low levels of estrogen stimulates FSH production
follicle stimulating hormone
- initiates follicular growth and stimulates the maturation of the graafian follicles
- secreted by anterior pituitary gland
- levels low in childhood and slightly higher after menopause
- levels decline in late follicular phase and slight increase at end of luteal phase
corpus albcians
scar from previous corpus luteum
asymptomatic
hyperechoic focus within the ovary
differential: cystic teratoma
proliferation phase of the endo
- overlaps the postmenstruation phase and occurs from days 6-14
- increasing estrogen levels regenerates the functional layer
- coincides with the follicular phase of the ovary
- early phase 4-6mm
- late phase 6-10mm
luteal phase of the ovary
- days 15-28
- corpus luteum grows for 7-8 days, secreting some estrogen and an increasing amount of progesterone
- if ovum is fertilized, the corpus luteum will continue to secrete progesterone
- if fertilization does not occur, corpus luteum regresses after 9 days and progesterone levels decrease
postmenopause without hormone replacement
- uterus generally decreases in length and width
- endo thickness should not exceed 8mm in asymptomatic patients or 5mm with vaginal bleeding
- ovaries atrophy and may be difficult to visualize
- decrease in estrogen can shorten the vagina and decreasecervical mucus
amenorrhea
absence of menstruation
endometrium
- thickness should not exceed 14 mm
- thickness of the postmenopausal endo without hormone replacement therapy should not exceed 8mm and is consistently benign when measuring 5mm or less
- fluid within the endo cavity is not included in the measurement of the endo thickness
mittelschmerz
used to describe pelvic pain preceding ovulation
ovulatory phase of the ovary
- occurs at the rupture of the graafian follicle-day 14
- pelvic pain increases over the ovulatory ovary (mittelschmerz)
- minimal amount of cul-de-sac fluid
estrogen
- primary female sex hormone
- naturally occuring estrogens include estradiol, estroil, and estrone
- primarily produced by developing follicles and the placenta
- FSH and luteinizing hormone stimulate the production of estrogen in ovaries
- breast, liver, and adrenal glands produce small amounts
- promotes secondary sex characteristics, accelerates growth in height and metabolism, reduces muscle mass, stimulates endo growth and proliferation, and increases uterine growth
secretory phase of the endo
- aka postovulatory or premenstrual phase
- days 15-28
- progestrone level increase stimulates changes in endo
- 7-14mm
polymenorrhea
time between monthly menstrual cycles that is fewer than 21 days
levonorgestrel implants
- inhibits ovulation and thickens cervical mucus
- thin capsule is placed under the skin
- lasts 5 yrs
- ovulatory phase should not occur
- endo appears as a thin echogenic line
follicular phase of ovary
- begins at strat of menstruation
- ends at ovulation
- generally 14 days
- FSH stimulates the growth of primary follicles
- dominant follicle will grow 2-3 mm/day
- estrogen levels increase
- days 1-5
- days 6-13
intrauterine device
- foreign body is placed in endo cavity at level of fundus and superior corpus
- paraguard- copper T shape
- mirena- hormone releasing plasctic T shape
- risks: infection, perforation, attachment to the basal layer
- ovulation and formation of a corpus luteum continue
precocious puberty
- early pubic hair, breast, or genital development, early maturation or from other conditons
- menstruation in girls before 10 years
- functional ovarian cysts
- pubic hair or genital enlargement in boys before 9 years
- elevated hormone levels indicate the possible presence of a hypothalamus, gonad, or adrenal gland neoplasm
dysmenorrhea
painful menses
simple cyst
- premenarche: follicular in origin resulting from excessive hormones
- menarche: failure of a dominant follicle to rupture
- postmenopausal: follicular in orgin
- asymptomatic
- pelvic pain
- irregular menses
- anechoic, smooth walls, posterior enhancement, most measure < 5cm
- differential: serous cystadenoma, paraovarian cyst, hydrosalpinx, bladder diverticulum
precocious pseudopuberty
- early breast development
- adrenal or ovarian mass can secrete excess estrogen
- uterine cervix is larger than the fundus
- normal ovaries without functional follicles
corpus luteum cyst
- small, irregular anechoic structure
- thick, irregular wall margins
- may contain internal echoes
- anechoic mass demonstrates peripheral hypervascularity (ring of fire)
postmenopause with hormone replacement
includes both estrogen and progesterone
endo varies in thickness but should measure <8mm in diameter
atrophy of the ovaries is not as prevalent
estradiol
during pregnancy estradiol levels will steadily rise
small amounts are present in the adrenal cortex and arterial walls
functional cyst
- benign cyst that respond to hormonal stimulation
- asymptomatic
- pelvic pain
- anechoic ovarian mass measuring < 3cm
- smooth wall margins
- differential: paraovarian cyst, hydrosalpinx, bladder diverticulum
oligomenorrhea
time between monthly menstrual cycles that exceeds 30 days
depot-medroxyprogesterone acetate
- inhibits ovulation and thickens cervical mucus
- intramuscular injection every 3 months
- ovulatory phase should not occur
- endo appears as a thin echogenic line
menorrhagia
abnormally heavy or long menses
physiology of ovaries
- 200,000 primary follicles
- secretion of FSH stimulates follicular development
- follicles will fill with fluid and secrete increasing amounts of estrogen
- 5 to 11 follicles will begin to develop, with one reaching maturity each cycle
- ovulation is regulated by the hypothalamus
- LH peak 10 to 12 hours before ovulation
- a surge in LH accomplished by a smaller FSH surge triggers ovulation
menstrual phase of the endometrium
- occurs days 1-5
- functional layer undergoes necrosis from a decrease in estrogen and progesterone levels
- early phase 4-8mm
- late phase 2-3mm
progesterone
- levels are low in childhood and postmenopause
- produced in the adrenal glands, corpus luteum, brain, and placenta
- increasing amounts of progesterone are produced during pregnancy
- levels low during preovulatory phase, increase after ovulation, and remain elevated during the luteal phase
- prepares endo for possible implantation or starting the nest menstrual cycle
normally physiology of female pelvis
- menstruation generally occurs between 11 and 13 years of age
- cessation of menstruation usually occurs around age 50
- mentrual cycle ranges 21 and 35 days, average 28 days
- rupture of graafian follicle each cycle
- menstruation depends on functional integrity of hypothalamus, pituitary gland, and ovarian axis.
hemorrhagic cyst
- rupture of a blood vessel at ovulation
- severe acute pelvic pain
- nausea/ vomting
- low-grade fever
- complex, hypoechoic, possible septations, fluid in cul-de-sac
- differential: torsion, cystadenoma, ectopic pregnancy, theca lutein cyst