Physiology of the Auditory and Vestibular Systems Flashcards
Describe the basilar membrane near the oval and round windows versus near the helicotrema?
Oval/Round Windows: narrow and stiff
Helicotrema: wider and more flexible
What do high frequency sounds cause at the basilar membrane?
Greater deflection of the basilar membrane where it is narrow and stiff
What do lower frequency sounds cause at the basilar membrane?
Greater deflection of the basilar membrane where it is loose and flexible
How is the frequency of sound (pitch) coded?
Coded by where along the basilar membrane there is the greatest deflection
Define the auditory system
Detects sound and uses acoustic cues to identify and locate sound sources in the environment
Define sound
Oscillations of air pressure that vary rapidly with time
Define amplitude
Sound pressure (intensity) specified by a scale of sound pressure level (SPL) in decibels (dB)
Define frequency
Number of oscillations of air pressure per second (Hz)
What is tonotopy? What does this apply to?
Applies to the inner ear, with distinct locations interpreting discrete frequencies
What does the vibration of the basilar membrane create?
Creates a pressure differential, which results in a shearing force against the stationary tectorial membrane, causing the stereocilia of the outer hair cells to be displaced in that plane
When does depolarization of the cell occur?
When cation channels open at the apex of the stereocilia
How are stereocilia connected and what do these connections do?
Connected to each other via tip links that transmit force to an elastic gating spring, which in turn, opens the TRPA1 channels
How fast can hair cells respond to a stimulus?
50 microseconds
What is endolymph?
Potassium-rich fluid filling the cochlear duct and membranous labyrinth; bathes the apical end of the hair cells; found in scala media, produced by stria vascularis
Similar to intracellular fluid
What is perilymph?
Potassium-poor fluid that bathes the basal end of the cochlear hair cells; found in scala vestibuli and scala tympani
Similar to extracellular fluid