Physiology Of The ANS (DSA)

Question 1

Define the axo-dendritic synpase

Answer 1

Most common
Synapse between pre-synaptic terminal of an axon and the post-synaptic membrane of a dendrite
Usually excitatory

Question 2

What does the pre-synaptic terminal contain

Answer 2

Increased mitochondria
Increased vesicles
Storage of neuro transmitter

Question 3

What does the AP in an axon cause to happen in the pre-synaptic cleft

Answer 3

Ca VGC to open, allowing influx of Ca and conformational change of vesicles which allows for them to dock to the pre-synaptic membrane and release their contents

Question 4

Define the ionotropic receptor and its two subclasses and affects

Answer 4

Sensitive to ions

Sensitive to Ca or Na - allows them into post-synaptic cell and causes an EPSP

Sensitive to Cl - allows it into cell and causes an IPSP

Question 5

Define metabotropic receptors and what it does

Answer 5

Uses a secondary pathway to elicit a response

Is secondary pathway is IP3/DAG - receptor is calcium

Question 6

What are the two ways to get rid of neuro transmitter from synaptic cleft

Answer 6

1. Acetylcholinesterase - destroy ACh

2. Reuptake

Question 7

What is the unexpected stretch of a skeletal muscle sensed by and how does this work in the SC

Answer 7

Muscles spindles that send an afferent signal to the SC via DRG and synapse directly onto the alpha-motor neuron

Question 8

The afferent signal from a stretch reflex will cause what to be done in the efferent nerves

Answer 8

An AP that will cause the release of ACh at NMJ and movement of muscle

Question 9

What does the Gi do when told to activate by ACh from parasympathetic NVS

Answer 9

Inhibits AC which means less cAMP and increased K out of cells and a slow HR