Physiology of aging patients Flashcards
1
Q
Nervous system changes
A
- Decreased gray/white matter
- Decreased neurotransmitters (acetylcholine, dopamine)
- Decreased epidural space
- Decreased CSF volume
- Increased permeability of dura mater
2
Q
CV system changes
A
- Decreased ventricular compliance (so preload depends more on atrial kick)
- Decreased beta-receptor responsiveness
- Increased sympathetic nervous system activity
- Increased stiffness of large arteries
3
Q
Respiratory system changes
A
- Decreased vital capacity
- Increased residual volume
- Increased closing capacity
- Increased anatomic dead space
- Increased lung compliance
- Increased pulmonary vascular resistance
4
Q
Hepatic system changes
A
- Decreased hepatic blood flow