Physiology of aging patients Flashcards

1
Q

Nervous system changes

A
  • Decreased gray/white matter
  • Decreased neurotransmitters (acetylcholine, dopamine)
  • Decreased epidural space
  • Decreased CSF volume
  • Increased permeability of dura mater
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2
Q

CV system changes

A
  • Decreased ventricular compliance (so preload depends more on atrial kick)
  • Decreased beta-receptor responsiveness
  • Increased sympathetic nervous system activity
  • Increased stiffness of large arteries
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3
Q

Respiratory system changes

A
  • Decreased vital capacity
  • Increased residual volume
  • Increased closing capacity
  • Increased anatomic dead space
  • Increased lung compliance
  • Increased pulmonary vascular resistance
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4
Q

Hepatic system changes

A
  • Decreased hepatic blood flow
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